Interactor 1: Q8IPE8 (Q8IPE8)
Trifunctional enzyme subunit alpha, mitochondrial (EC 1.1.1.211) (EC 4.2.1.17) (Monolysocardiolipin acyltransferase) (TP-alpha)
Gene: Mtpalpha

Interactor 2: Q9W1H8 (Q9W1H8)
acetyl-CoA C-acyltransferase (EC 2.3.1.16)
Gene: Mtpbeta

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains 3HCDH~Thiolase_N, 3HCDH_N~Thiolase_N, ECH_1~Thiolase_C, ECH_1~Thiolase_N
Common GO terms GO:0005739 - mitochondrion
GO:0006635 - fatty acid beta-oxidation
GO:0008340 - determination of adult lifespan
GO:0016507 - mitochondrial fatty acid beta-oxidation multienzyme complex
GO:0016509 - long-chain (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 744
Dm

1 469
+ Hs
+ Mm
+ Ec
+ Hs
+ Dm
+ At

Service provided by Combinatics, Japan

Last updated: 11Aug2025