HitPredict

Interactor 1: SPAG5 (Q96R06)
Sperm-associated antigen 5 (Astrin) (Deepest) (Mitotic spindle-associated protein p126) (MAP126)
Gene: SPAG5

Interactor 2: X5DP31 (X5DP31)
Aryl-hydrocarbon receptor nuclear translocator 2 isoform E
Gene: ARNT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	24722188
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1193 Hs			1 660
+	Hs
		1300725 SPAG5_HUMAN (1-1193): 4.62e-140: 457: 100.00		ARNT2_HUMAN (1-658): 0: 631: 89.88
+	Hs
		649050 MYH10_HUMAN (837-1188): 2.71e-11: 70.7: 11.33		ARNT_HUMAN (4-658): 0: 545: 52.40
+	Hs
		649049 MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04		ARNT_HUMAN (4-658): 0: 545: 52.40
+	Hs
		522551 MYH1_HUMAN (287-962): 1.25e-30: 133: 11.18		HIF1A_HUMAN (48-604): 2.8e-127: 397: 20.46
+	Hs
		1085739 MYH4_HUMAN (291-1062): 2.67e-30: 132: 12.19		HIF1A_HUMAN (48-604): 2.8e-127: 397: 20.46
+	Hs
		502916 MYH3_HUMAN (173-1134): 9.39e-30: 131: 11.22		HIF1A_HUMAN (48-604): 2.8e-127: 397: 20.46
+	Hs
		1085714 MYH2_HUMAN (192-1011): 9.96e-28: 124: 10.37		HIF1A_HUMAN (48-604): 2.8e-127: 397: 20.46
+	Hs
		528376 MYH6_HUMAN (958-1190): 3.59e-09: 63.7: 14.16		HIF1A_HUMAN (48-604): 2.8e-127: 397: 20.46
+	Dm
		1096484 MYSN_DROME (563-1192): 4.24e-23: 109: 11.48		SIMA_DROME (50-619): 4.16e-99: 334: 18.99
+	Hs
		254453 ROCK2_HUMAN (526-1193): 1.76e-21: 103: 11.92		AHR_HUMAN (32-589): 2.27e-105: 340: 15.46
+	Hs
		728911 ROCK1_HUMAN (546-1186): 1.44e-17: 90.8: 14.97		AHR_HUMAN (32-589): 2.27e-105: 340: 15.46
+	Hs
		725093 MYH9_HUMAN (873-1192): 7.59e-11: 69.1: 13.04		NCOA3_HUMAN (47-656): 2.57e-106: 353: 17.45