Interactor 1: SMC6 (Q96SB8)
Structural maintenance of chromosomes protein 6 (SMC protein 6) (SMC-6) (hSMC6)
Gene: SMC6

Interactor 2: RAD18 (Q9NS91)
E3 ubiquitin-protein ligase RAD18 (EC 2.3.2.27) (Postreplication repair protein RAD18) (hHR18) (hRAD18) (RING finger protein 73) (RING-type E3 ubiquitin transferase RAD18)
Gene: RAD18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 26496610
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003684 - damaged DNA binding
GO:0003697 - single-stranded DNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0006974 - DNA damage response
and 3 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1091
Hs

1 495
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024