Protein: SPT3
SAGA complex subunit SPT3 (Positive regulator of Ty transcription) (Suppressor of Ty protein 3)

Gene: SPT3
Organism: Saccharomyces cerevisiae S288C
Interactions: 50
UniProt ID: P06844

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0001403 - invasive growth in response to glucose limitation
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

449436

TBP
TATA-box-binding protein

6

3

Small-scale

0.938

High

449474

TAF10
SAGA complex/transcription factor TFIID complex subunit TAF10

5

6

Small-scale

0.892

High

449466

ADA2
SAGA complex subunit ADA2

17

4

Small-scale

0.763

High

449451

SPT7
SAGA complex subunit SPT7

18

9

Small-scale

0.762

High

449475

HFI1
SAGA complex subunit HFI1

12

1

Small-scale

0.757

High

449463

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

10

5

Small-scale

0.756

High

449461

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

10

3

Small-scale

0.751

High

449468

GCN5
Histone acetyltransferase GCN5

7

5

Small-scale

0.748

High

449469

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

8

6

Small-scale

0.743

High

449456

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

7

3

Small-scale

0.741

High

449472

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

7

6

Small-scale

0.739

High

449446

NGG1
SAGA complex subunit NGG1

6

1

Small-scale

0.729

High

449454

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

6

6

Small-scale

0.729

High

449462

SPT20
SAGA complex subunit SPT20

12

0

Small-scale

0.726

High

449457

SPT8
SAGA complex subunit SPT8

7

0

Small-scale

0.714

High

449439

SGF29
SAGA complex subunit SGF29

5

2

Small-scale

0.714

High

449464

SGF73
SAGA complex subunit SGF73

5

3

Small-scale

0.712

High

449479

SUS1
SAGA complex subunit SUS1

4

2

Small-scale

0.697

High

449467

SGF11
SAGA complex subunit SGF11

5

0

Small-scale

0.678

High

395211

GCN4
General control transcription factor GCN4

3

1

Small-scale

0.647

High

449442

BTAF1
TATA-binding protein-associated factor MOT1

2

1

Small-scale

0.584

High

449441

XPO1
Exportin-1

1

1

High-throughput

0.536

High

449473

CTI6
Histone deacetylase complex subunit CTI6

1

1

Small-scale

0.515

High

449437

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.513

High

449458

TAF1
Transcription initiation factor TFIID subunit 1

1

2

Small-scale

0.501

High

449465

NOP13
Nucleolar protein 13

1

0

High-throughput

0.493

High

449477

HAT1
Histone acetyltransferase type B catalytic subunit

1

0

High-throughput

0.493

High

408378

GAL4
Regulatory protein GAL4

1

1

Small-scale

0.481

High

449471

TAF7
Transcription initiation factor TFIID subunit 7

1

3

High-throughput

0.479

High

449440

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

449443

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

449444

ASF1
Histone chaperone ASF1

1

0

Small-scale

0.458

High

449445

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.458

High

449447

CHD1
Chromo domain-containing protein 1

1

0

Small-scale

0.458

High

449452

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

449455

RCK1
Serine/threonine-protein kinase RCK1

1

0

High-throughput

0.458

High

449459

NU192
Nucleoporin NUP192

1

0

High-throughput

0.458

High

449460

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

449470

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

449478

SMC6
Structural maintenance of chromosomes protein 6

1

0

High-throughput

0.458

High

449434

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

449435

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

449449

MSN2
Zinc finger protein MSN2

1

1

High-throughput

0.445

High

449450

MSN4
Zinc finger protein MSN4

1

1

High-throughput

0.445

High

449453

SET3
SET domain-containing protein 3

1

1

High-throughput

0.445

High

380920

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

448114

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

449438

AFT1
Iron-regulated transcriptional activator AFT1

1

0

High-throughput

0.426

High

449476

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.426

High

449448

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025