HitPredict

Interactor 1: EIF3C (Q99613)
Eukaryotic translation initiation factor 3 subunit C (eIF3c) (Eukaryotic translation initiation factor 3 subunit 8) (eIF3 p110)
Gene: EIF3C

Interactor 2: EIF3K (Q9UBQ5)
Eukaryotic translation initiation factor 3 subunit K (eIF3k) (Eukaryotic translation initiation factor 3 subunit 12) (Muscle-specific gene M9 protein) (PLAC-24) (eIF-3 p25) (eIF-3 p28)
Gene: EIF3K

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	1.00	0.893

The method score is based on:

Property	Details
Experiments	14519125, 24981860, 33961781, 23623729
Identification Methods	pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	CSN8_PSD8_EIF3K~PCI
Common GO terms	GO:0001732 - formation of cytoplasmic translation initiation complex GO:0003723 - RNA binding GO:0003743 - translation initiation factor activity GO:0005829 - cytosol GO:0005852 - eukaryotic translation initiation factor 3 complex and 4 others more... GO:0006413 - translational initiation GO:0016282 - eukaryotic 43S preinitiation complex GO:0033290 - eukaryotic 48S preinitiation complex GO:0043022 - ribosome binding
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	913
Hs

1	218

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024