HitPredict

Interactor 1: MY18B (Q8IUG5)
Unconventional myosin-XVIIIb
Gene: MYO18B

Interactor 2: SCN8A (Q9UQD0)
Sodium channel protein type 8 subunit alpha (Sodium channel protein type VIII subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.6)
Gene: SCN8A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37071682
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0030018 - Z disc
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2567 Hs			1 1980
+	Hs
		776871 MYH11_HUMAN (1278-2268): 3.43e-58: 226: 13.34		SCN8A_HUMAN (1-1980): 0: 1996: 100.00
+	Mm
		73109 MYH9_MOUSE (1673-2558): 9.36e-50: 198: 13.29		SCN2A_MOUSE (1-1979): 0: 1905: 73.20
+	Rn
		415176 MYH10_RAT (1696-2558): 1.86e-46: 187: 13.73		SCN2A_RAT (1-1979): 0: 1897: 73.00
+	Rn
		147604 MYH10_RAT (1696-2558): 1.86e-46: 187: 13.73		SCN9A_RAT (4-1974): 0: 1841: 68.48
+	Rn
		147603 MYH9_RAT (1699-2558): 5.36e-46: 186: 12.29		SCN9A_RAT (4-1974): 0: 1841: 68.48
+	Rn
		465779 MYH10_RAT (1696-2558): 1.86e-46: 187: 13.73		SCN3A_RAT (1-1979): 0: 1809: 72.27
+	Rn
		465777 MYH9_RAT (1699-2558): 5.36e-46: 186: 12.29		SCN3A_RAT (1-1979): 0: 1809: 72.27
+	Rn
		1224344 MYH10_RAT (1696-2558): 1.86e-46: 187: 13.73		SCNAA_RAT (6-1971): 0: 1718: 52.98
+	Rn
		1224281 MYH9_RAT (1699-2558): 5.36e-46: 186: 12.29		SCNAA_RAT (6-1971): 0: 1718: 52.98
+	Hs
		1119230 MY18A_HUMAN (1978-2567): 1.88e-34: 148: 10.23		CAC1C_HUMAN (350-549): 1.56e-09: 65.7: 17.39