HitPredict

Interactor 1: AKAP9 (Q99996)
A-kinase anchor protein 9 (AKAP-9) (A-kinase anchor protein 350 kDa) (AKAP 350) (hgAKAP 350) (A-kinase anchor protein 450 kDa) (AKAP 450) (AKAP 120-like protein) (Centrosome- and Golgi-localized PKN-associated protein) (CG-NAP) (Protein hyperion) (Protein kinase A-anchoring protein 9) (PRKA9) (Protein yotiao)
Gene: AKAP9

Interactor 2: TNIK (Q9UKE5)
TRAF2 and NCK-interacting protein kinase (EC 2.7.11.1)
Gene: TNIK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.590

Property	Details
Experiments	17043677, unassigned1973
Identification Methods	two hybrid, two hybrid fragment pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3907 Hs			1 1360
+	Mm
		949334 AKAP9_MOUSE (1-3907): 0: 725: 65.51		TNIK_MOUSE (1-1360): 0: 1208: 96.10
+	Hs
		1034641 GOGA4_HUMAN (2363-3904): 4.27e-51: 203: 9.92		TNIK_HUMAN (1-1360): 0: 1235: 100.00
+	Hs
		1356411 MACF1_HUMAN (883-3859): 6.57e-41: 170: 8.89		TNIK_HUMAN (1-1360): 0: 1235: 100.00
+	Mm
		949395 DYST_MOUSE (793-3768): 2.53e-41: 172: 9.74		TNIK_MOUSE (1-1360): 0: 1208: 96.10
+	Hs
		974168 DYST_HUMAN (19-1901): 3.23e-25: 118: 9.49		TNIK_HUMAN (1-1360): 0: 1235: 100.00
+	Hs
		1023100 AKAP9_HUMAN (1-3907): 0: 878: 100.00		STK4_HUMAN (5-482): 7.72e-121: 387: 33.06
+	Hs
		131598 AKAP9_HUMAN (1-3907): 0: 878: 100.00		STK25_HUMAN (20-410): 8.77e-113: 362: 37.91
+	Mm
		956963 CE290_MOUSE (1750-3892): 3.91e-53: 210: 9.27		M4K4_MOUSE (1-1360): 0: 946: 58.91
+	Hs
		1071717 MACF1_HUMAN (883-3859): 6.57e-41: 170: 8.89		KS6A2_HUMAN (10-709): 1.39e-140: 449: 18.52
+	Hs
		1313528 CP250_HUMAN (2-1330): 1.53e-46: 189: 10.71		SIK2_HUMAN (15-915): 3.97e-124: 410: 14.70
+	Hs
		1357666 MACF1_HUMAN (883-3859): 6.57e-41: 170: 8.89		MAST1_HUMAN (2-1051): 2.7e-124: 424: 14.80
+	Hs
		166768 CE290_HUMAN (2108-3900): 1.69e-42: 175: 10.38		NEK1_HUMAN (23-999): 1.84e-122: 413: 16.85
+	Hs
		647985 MACF1_HUMAN (883-3859): 6.57e-41: 170: 8.89		MARK3_HUMAN (3-675): 1.72e-124: 406: 16.37
+	Hs
		528369 MYH6_HUMAN (571-1660): 2.29e-37: 158: 10.35		STK4_HUMAN (5-482): 7.72e-121: 387: 33.06
+	Hs
		528371 MYH6_HUMAN (571-1660): 2.29e-37: 158: 10.35		STK3_HUMAN (4-485): 1.79e-115: 372: 29.28
+	Hs
		502911 MYH3_HUMAN (2796-3744): 4.53e-31: 137: 11.53		STK4_HUMAN (5-482): 7.72e-121: 387: 33.06
+	Hs
		502912 MYH3_HUMAN (2796-3744): 4.53e-31: 137: 11.53		STK3_HUMAN (4-485): 1.79e-115: 372: 29.28
+	Hs
		974064 DYST_HUMAN (19-1901): 3.23e-25: 118: 9.49		STK3_HUMAN (4-485): 1.79e-115: 372: 29.28
+	Hs
		522609 MYH7_HUMAN (3369-3901): 1.83e-15: 86.3: 8.52		STK4_HUMAN (5-482): 7.72e-121: 387: 33.06
+	Hs
		522610 MYH7_HUMAN (3369-3901): 1.83e-15: 86.3: 8.52		STK3_HUMAN (4-485): 1.79e-115: 372: 29.28