Protein: CCNB2
G2/mitotic-specific cyclin-B2

Gene: CCNB2
Organism: Homo sapiens
Interactions: 60
UniProt ID: O95067

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0001701 - in utero embryonic development
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

325458

CDK1
Cyclin-dependent kinase 1

9

20

Small-scale

0.975

High

325466

CDK2
Cyclin-dependent kinase 2

6

20

High-throughput

0.949

High

325500

PMYT1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

4

12

High-throughput

0.909

High

325472

CDN1A
Cyclin-dependent kinase inhibitor 1

2

15

High-throughput

0.812

High

325473

CDN1B
Cyclin-dependent kinase inhibitor 1B

2

15

High-throughput

0.811

High

325463

CSK22
Casein kinase II subunit alpha'

1

20

High-throughput

0.691

High

325475

CDN1C
Cyclin-dependent kinase inhibitor 1C

1

15

High-throughput

0.691

High

325482

CDK17
Cyclin-dependent kinase 17

1

20

High-throughput

0.691

High

325483

PCM1
Pericentriolar material 1 protein

4

1

High-throughput

0.687

High

325469

CKS2
Cyclin-dependent kinases regulatory subunit 2

3

20

Small-scale

0.670

High

325478

CKS1
Cyclin-dependent kinases regulatory subunit 1

3

20

Small-scale

0.670

High

325455

VAPB
Vesicle-associated membrane protein-associated protein B/C

3

1

High-throughput

0.667

High

325507

GMPPB
Mannose-1-phosphate guanylyltransferase catalytic subunit beta

3

1

High-throughput

0.667

High

325465

CRHBP
Corticotropin-releasing factor-binding protein

4

0

High-throughput

0.661

High

325496

WDFY1
WD repeat and FYVE domain-containing protein 1

2

2

High-throughput

0.628

High

325505

VAPA
Vesicle-associated membrane protein-associated protein A

2

1

High-throughput

0.628

High

325477

PLK1
Serine/threonine-protein kinase PLK1

1

2

High-throughput

0.618

High

325481

CDK5
Cyclin-dependent kinase 5

1

20

High-throughput

0.618

High

60700

F234B
Protein FAM234B

2

0

High-throughput

0.602

High

325464

FLNA
Filamin-A

1

1

Small-scale

0.597

High

325498

NIN
Ninein

2

1

High-throughput

0.584

High

325474

MCM2
DNA replication licensing factor MCM2

1

4

High-throughput

0.536

High

193077

DDX3Y
ATP-dependent RNA helicase DDX3Y

1

2

High-throughput

0.536

High

325454

SCAF4
SR-related and CTD-associated factor 4

1

1

High-throughput

0.536

High

325468

MPIP3
M-phase inducer phosphatase 3

1

8

High-throughput

0.536

High

325480

SKP1
S-phase kinase-associated protein 1

1

3

High-throughput

0.536

High

325494

K2C73
Keratin, type II cytoskeletal 73

1

1

High-throughput

0.536

High

325508

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

1

1

High-throughput

0.536

High

325459

F163B
Protein FAM163B

1

0

High-throughput

0.513

High

325462

CREB1
Cyclic AMP-responsive element-binding protein 1

1

0

High-throughput

0.513

High

325485

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

0

High-throughput

0.513

High

325487

NCBP3
Nuclear cap-binding protein subunit 3

1

0

High-throughput

0.513

High

325488

TMM53
Transmembrane protein 53

1

0

High-throughput

0.513

High

325492

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.513

High

325471

TGFR2
TGF-beta receptor type-2

1

1

Small-scale

0.501

High

172354

XPO1
Exportin-1

1

5

High-throughput

0.479

High

325460

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

325461

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

325467

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

325479

H4
Histone H4

1

2

High-throughput

0.479

High

325484

CCDC6
Coiled-coil domain-containing protein 6

1

1

High-throughput

0.479

High

325491

CE128
Centrosomal protein of 128 kDa

1

1

High-throughput

0.479

High

325501

TSYL2
Testis-specific Y-encoded-like protein 2

1

4

Small-scale

0.479

High

325503

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

325506

ZO2
Tight junction protein 2

1

1

High-throughput

0.479

High

163880

NDC80
Kinetochore protein NDC80 homolog

1

0

High-throughput

0.458

High

325456

EYA4
Protein phosphatase EYA4

1

0

High-throughput

0.458

High

325457

RASK
GTPase KRas

1

0

High-throughput

0.458

High

325486

CCD14
Coiled-coil domain-containing protein 14

1

0

High-throughput

0.458

High

325495

MIB1
E3 ubiquitin-protein ligase MIB1

1

0

High-throughput

0.458

High

325499

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.458

High

325504

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.458

High

325470

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

325489

FBX42
F-box only protein 42

1

2

High-throughput

0.437

High

325490

LMBRL
Protein LMBR1L

1

1

High-throughput

0.437

High

262195

SCN2B
Sodium channel regulatory subunit beta-2

1

1

High-throughput

0.407

High

325497

S22AF
Solute carrier family 22 member 15

1

1

High-throughput

0.407

High

325502

GHITM
Growth hormone-inducible transmembrane protein

2

0

High-throughput

0.328

High

325476

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

325493

VSIG1
V-set and immunoglobulin domain-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025