Protein: CCNE2
G1/S-specific cyclin-E2

Gene: CCNE2
Organism: Homo sapiens
Interactions: 28
UniProt ID: O96020

Gene Ontology (top 5):
GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000723 - telomere maintenance
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

355336

CDK2
Cyclin-dependent kinase 2

12

20

Small-scale

0.984

High

355337

CDN1A
Cyclin-dependent kinase inhibitor 1

10

20

Small-scale

0.975

High

355339

CDN1B
Cyclin-dependent kinase inhibitor 1B

4

20

Small-scale

0.910

High

355344

CDK3
Cyclin-dependent kinase 3

4

20

Small-scale

0.902

High

355333

CDK1
Cyclin-dependent kinase 1

2

20

High-throughput

0.789

High

355335

PCNA
Proliferating cell nuclear antigen

3

5

High-throughput

0.667

High

355340

CDN1C
Cyclin-dependent kinase inhibitor 1C

1

20

Small-scale

0.656

High

355343

CKS1
Cyclin-dependent kinases regulatory subunit 1

2

20

High-throughput

0.628

High

355341

CDK9
Cyclin-dependent kinase 9

1

20

High-throughput

0.618

High

355349

CDK10
Cyclin-dependent kinase 10

1

20

High-throughput

0.618

High

355345

H11
Histone H1.1

1

14

Small-scale

0.561

High

355351

FBXW7
F-box/WD repeat-containing protein 7

1

5

Small-scale

0.561

High

355354

ORC3
Origin recognition complex subunit 3

1

2

High-throughput

0.536

High

355347

TFDP2
Transcription factor Dp-2

1

7

High-throughput

0.536

High

355332

ITB1
Integrin beta-1

1

1

High-throughput

0.515

High

355334

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

2

High-throughput

0.515

High

355355

RALY
RNA-binding protein Raly

1

1

High-throughput

0.515

High

355331

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

355356

SCML2
Sex comb on midleg-like protein 2

1

1

Small-scale

0.500

High

355338

HD
Huntingtin

1

0

High-throughput

0.493

High

355346

RBL2
Retinoblastoma-like protein 2

1

14

Small-scale

0.484

High

355357

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

355342

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

2

Small-scale

0.479

High

355348

KIF14
Kinesin-like protein KIF14

1

1

High-throughput

0.479

High

355353

CHD8
Chromodomain-helicase-DNA-binding protein 8

1

2

Small-scale

0.445

High

355350

ZDH17
Palmitoyltransferase ZDHHC17

1

2

High-throughput

0.439

High

355352

T3HPD
Trans-3-hydroxy-L-proline dehydratase

3

0

High-throughput

0.347

High

301290

WFS1
Wolframin

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025