HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30745168, 35530310
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0034774 - secretory granule lumen GO:1904813 - ficolin-1-rich granule lumen
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 310 Hs			1 548
+	Hs
		131057 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		TCPH_HUMAN (9-538): 0: 564: 26.39
+	Hs
		130795 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		TCPG_HUMAN (10-547): 0: 558: 28.21
+	Hs
		842983 CSN5_HUMAN (1-305): 6.24e-83: 255: 28.35		TCPQ_HUMAN (1-548): 0: 616: 100.00
+	Hs
		130793 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		TCPE_HUMAN (2-524): 0: 535: 29.62
+	Hs
		130803 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		TCPD_HUMAN (19-525): 0: 530: 28.24
+	Hs
		130732 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Sc
		792374 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		TCPH_YEAST (7-542): 0: 534: 28.34
+	Hs
		843314 CSN5_HUMAN (1-305): 6.24e-83: 255: 28.35		TCPD_HUMAN (19-525): 0: 530: 28.24
+	Hs
		573402 CSN5_HUMAN (1-305): 6.24e-83: 255: 28.35		TCPA_HUMAN (21-541): 0: 528: 29.89
+	Sc
		797450 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		TCPQ_YEAST (1-548): 4.9e-163: 477: 45.69
+	Hs
		317717 STABP_HUMAN (17-199): 5.28e-44: 157: 17.84		TCPE_HUMAN (2-524): 0: 535: 29.62