HitPredict

Interactor 1: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Interactor 2: NDE1 (Q9NXR1)
Nuclear distribution protein nudE homolog 1 (NudE)
Gene: NDE1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	24722188
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome GO:0005829 - cytosol GO:0005874 - microtubule
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 669 Hs			1 335
+	Hs
		1310243 LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00		X5DP35_HUMAN (1-268): 2.32e-50: 172: 98.88
+	Hs
		1326043 MTCL1_HUMAN (56-644): 5.72e-34: 141: 14.24		NDEL1_HUMAN (3-316): 1.44e-65: 212: 56.78
+	Hs
		724989 LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00		MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18
+	Hs
		1012572 CGNL1_HUMAN (321-645): 5.23e-13: 74.7: 21.88		NDE1_HUMAN (1-335): 2.68e-70: 224: 100.00
+	Mm
		139900 DCTN1_MOUSE (88-572): 4.8e-12: 71.6: 11.02		NDEL1_MOUSE (3-316): 7.82e-68: 217: 57.73
+	Cl
		47357 F1PHV6_CANLF (75-665): 5.04e-25: 113: 12.98		A0A8I3PJA6_CANLF (4-255): 9.4e-43: 159: 14.82
+	Rn
		222472 MRCKA_RAT (185-663): 4.24e-19: 94.3: 11.02		MRCKA_RAT (2-319): 1.69e-43: 162: 15.48
+	Hs
		787920 ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Hs
		61732 A6H8W8_HUMAN (71-636): 7.43e-22: 103: 13.52		EPS15_HUMAN (4-255): 3.09e-39: 149: 14.44
+	Rn
		92844 ITSN1_RAT (80-651): 3.99e-22: 104: 13.56		E9PSY8_RAT (4-255): 1.13e-35: 139: 13.76
+	Hs
		725035 MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02		MYH9_HUMAN (2-221): 3.6e-33: 131: 18.18
+	Hs
		522657 MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32		MYH7_HUMAN (3-226): 2.27e-35: 138: 12.95
+	Hs
		502933 MYH3_HUMAN (321-655): 9.39e-13: 74: 14.93		MYH4_HUMAN (3-226): 7.36e-35: 136: 13.39
+	Hs
		528432 MYH13_HUMAN (161-669): 3.57e-13: 75.4: 11.94		MYH8_HUMAN (3-226): 2.41e-33: 132: 12.95
+	Hs
		528435 MYH4_HUMAN (261-669): 1.55e-12: 73.1: 12.32		MYH8_HUMAN (3-226): 2.41e-33: 132: 12.95
+	Hs
		502901 MYH3_HUMAN (321-655): 9.39e-13: 74: 14.93		MYH6_HUMAN (3-226): 3.52e-33: 131: 13.39
+	Hs
		1078856 ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88		MYH14_HUMAN (2-211): 4.08e-18: 87.7: 17.62
+	Dm
		1303379 MYSN_DROME (321-639): 1.56e-12: 73.5: 17.45		MYSN_DROME (9-211): 1.49e-22: 100: 16.26
+	Rn
		222476 MRCKA_RAT (185-663): 4.24e-19: 94.3: 11.02		MRCKB_RAT (1-321): 3.25e-09: 60.3: 9.36