HitPredict

Interactor 1: NFIP1 (Q9BT67)
NEDD4 family-interacting protein 1 (Breast cancer-associated protein SGA-1M) (NEDD4 WW domain-binding protein 5) (Putative MAPK-activating protein PM13) (Putative NF-kappa-B-activating protein 164) (Putative NFKB and MAPK-activating protein)
Gene: NDFIP1

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36929005
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 221 Hs			1 400
+	Hs
		1311857 NFIP1_HUMAN (1-221): 1.9e-136: 383: 100.00		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		1294848 NFIP1_HUMAN (1-221): 1.9e-136: 383: 100.00		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Mm
		1208047 NFIP1_MOUSE (1-221): 1.54e-136: 383: 97.29		ITCH_MOUSE (119-356): 8.31e-59: 207: 15.66
+	Hs
		125686 NFIP1_HUMAN (1-221): 1.9e-136: 383: 100.00		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		808964 NFIP2_HUMAN (12-220): 5.72e-98: 290: 55.46		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1311860 NFIP1_HUMAN (1-221): 1.9e-136: 383: 100.00		SMUF1_HUMAN (55-362): 3.85e-51: 184: 16.62
+	Hs
		1327920 NFIP2_HUMAN (12-220): 5.72e-98: 290: 55.46		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		1294871 NFIP2_HUMAN (12-220): 5.72e-98: 290: 55.46		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		125746 NFIP2_HUMAN (12-220): 5.72e-98: 290: 55.46		WWP2_HUMAN (3-220): 6.4e-59: 207: 19.46
+	Hs
		808249 NFIP1_HUMAN (1-221): 1.9e-136: 383: 100.00		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Mm
		93279 NFIP1_MOUSE (1-221): 1.54e-136: 383: 97.29		E9PXB7_MOUSE (129-395): 7.76e-23: 102: 12.68
+	Rn
		1137274 NFIP1_RAT (1-221): 2.44e-135: 380: 97.74		NEDD4_RAT (129-328): 3.12e-22: 100: 11.65
+	Mm
		808368 NFIP1_MOUSE (1-221): 1.54e-136: 383: 97.29		NEDD4_MOUSE (129-328): 8.42e-21: 96.6: 10.44
+	Hs
		1299617 NFIP1_HUMAN (1-221): 1.9e-136: 383: 100.00		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Hs
		808291 NFIP2_HUMAN (12-220): 5.72e-98: 290: 55.46		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Dm
		1374794 Q9VVJ5_DROME (100-221): 4.9e-53: 173: 40.98		SUDX_DROME (115-386): 1.08e-56: 201: 15.39
+	Hs
		1299647 NFIP2_HUMAN (12-220): 5.72e-98: 290: 55.46		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Dm
		1360300 Q9VVJ5_DROME (100-221): 4.9e-53: 173: 40.98		SMUF1_DROME (124-208): 1.18e-18: 90.3: 24.71
+	Dm
		1374786 Q9VVJ5_DROME (100-221): 4.9e-53: 173: 40.98		NEDD4_DROME (4-326): 2.7e-13: 73.9: 9.66