Interactor 1: BIN1 (O00499)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1)
Gene: BIN1

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.707

The method score is based on:

Property Details
Experiments 31815296, 10380878, 15992821, 30253944
Identification Methods affinity chromatography technology, pull down, x-ray crystallography, two hybrid, anti bait coimmunoprecipitation, nuclear magnetic resonance
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0010564 - regulation of cell cycle process
GO:0090571 - RNA polymerase II transcription repressor complex
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 593
Hs

1 454
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024