Interactor 1: RCAF1 (Q9BUV8)
GEL complex subunit OPTI (Obligate partner of TMCO1 insertase) (Rab5-interacting protein) (RIP5) (Respirasome Complex Assembly Factor 1)
Gene: RAB5IF

Interactor 2: TMCO1 (Q9UM00)
Calcium load-activated calcium channel (CLAC channel) (GEL complex subunit TMCO1) (Transmembrane and coiled-coil domain-containing protein 1) (Transmembrane and coiled-coil domains protein 4) (Xenogeneic cross-immune protein PCIA3)
Gene: TMCO1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 0.90 0.656

The method score is based on:

Property Details
Experiments 35271311
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains EMC3_TMCO1~EMC6
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0160063 - multi-pass transmembrane protein insertion into ER membrane
GO:0160064 - multi-pass translocon complex
Homologous interactions 0

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Last updated: 15 Jul 2024