HitPredict

Interactor 1: IMA4 (O00505)
Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma)
Gene: KPNA3

Interactor 2: NOP56 (O00567)
Nucleolar protein 56 (Nucleolar protein 5A)
Gene: NOP56

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 594
+	Hs
		133234 IMA3_HUMAN (1-521): 1.68e-160: 468: 85.80		NOP56_HUMAN (1-594): 0: 661: 100.00
+	Hs
		133254 IMA7_HUMAN (1-520): 9.33e-140: 415: 46.54		NOP56_HUMAN (1-594): 0: 661: 100.00
+	Hs
		133237 IMA6_HUMAN (1-520): 1.1e-135: 405: 46.65		NOP56_HUMAN (1-594): 0: 661: 100.00
+	Hs
		133392 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		NOP56_HUMAN (1-594): 0: 661: 100.00
+	Sp
		293205 IMA2_SCHPO (9-521): 9.03e-137: 407: 46.14		NOP56_SCHPO (2-430): 0: 553: 55.43
+	Hs
		853524 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		NOP58_HUMAN (4-567): 0: 531: 35.39
+	Hs
		238749 IMA7_HUMAN (1-520): 9.33e-140: 415: 46.54		NOP58_HUMAN (4-567): 0: 531: 35.39
+	Hs
		853761 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		NOP58_HUMAN (4-567): 0: 531: 35.39
+	Sc
		972944 IMA1_YEAST (8-521): 1.35e-134: 402: 45.22		NOP56_YEAST (5-438): 1.95e-180: 521: 53.62
+	Sc
		972949 IMA1_YEAST (8-521): 1.35e-134: 402: 45.22		NOP58_YEAST (3-443): 3.77e-156: 459: 40.36
+	Hs
		853397 IMA1_HUMAN (3-521): 1.35e-143: 425: 48.49		PRP31_HUMAN (160-581): 1.53e-125: 380: 19.91
+	Hs
		853666 IMA5_HUMAN (5-520): 3.45e-133: 398: 45.52		PRP31_HUMAN (160-581): 1.53e-125: 380: 19.91
+	Dm
		1370645 Q9VRS0_DROME (97-485): 1.55e-71: 236: 37.95		Q9VM69_DROME (4-491): 4.2e-166: 484: 36.89