Interactor 1: MTNA (Q9BV20)
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (Mediator of RhoA-dependent invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)
Gene: MRI1

Interactor 2: MTNA (Q9BV20)
Methylthioribose-1-phosphate isomerase (M1Pi) (MTR-1-P isomerase) (EC 5.3.1.23) (Mediator of RhoA-dependent invasion) (S-methyl-5-thioribose-1-phosphate isomerase) (Translation initiation factor eIF-2B subunit alpha/beta/delta-like protein)
Gene: MRI1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.939

The method score is based on:

Property Details
Experiments 25416956, 16189514, 32296183, 19447967, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, two hybrid array, two hybrid prey pooling approach, two hybrid pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains IF-2B~IF-2B
Common GO terms GO:0001650 - fibrillar center
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0019284 - L-methionine salvage from S-adenosylmethionine
GO:0019509 - L-methionine salvage from methylthioadenosine
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 369
Hs

1 369
+ Sp
+ Hs
+ Hs
+ Sc
+ Hs
+ Hs
+ Dm
+ Sp
+ Hs
+ Sc
+ Sc
+ Hv
+ Sc
+ Sc

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Last updated: 15 Jul 2024