Interactor 1: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Interactor 2: PINK1 (Q9BXM7)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.924

The method score is based on:

Property Details
Experiments 30783609, 31300519, 14607334, 22280891, 22724072
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~Pkinase
Common GO terms GO:0000287 - magnesium ion binding
GO:0000422 - autophagy of mitochondrion
GO:0000423 - mitophagy
GO:0000785 - chromatin
GO:0002020 - protease binding
and 95 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 581
Hs

1 581
+ Mm
+ Hs
+ Hs
+ Dm
+ Hs
+ Rn
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ At

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Last updated: 15 Jul 2024