Protein: COPZ1
Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP)

Gene: COPZ1
Organism: Homo sapiens
Interactions: 171
UniProt ID: P61923

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0006890 - retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

902393

COPG1
Coatomer subunit gamma-1

8

20

Small-scale

0.969

High

863189

COPB
Coatomer subunit beta

5

20

Small-scale

0.926

High

818912

COPD
Coatomer subunit delta

2

3

High-throughput

0.811

High

902381

COPG2
Coatomer subunit gamma-2

2

20

High-throughput

0.811

High

902291

COPZ1
Coatomer subunit zeta-1

2

5

Small-scale

0.754

High

863395

COPA
Coatomer subunit alpha

3

5

Small-scale

0.670

High

149594

COPE
Coatomer subunit epsilon

3

2

High-throughput

0.667

High

833194

TMEDA
Transmembrane emp24 domain-containing protein 10

3

3

Small-scale

0.631

High

725408

COPB2
Coatomer subunit beta'

2

5

High-throughput

0.628

High

574639

ARF4
ADP-ribosylation factor 4

2

11

High-throughput

0.611

High

902297

ARF5
ADP-ribosylation factor 5

2

11

High-throughput

0.611

High

902356

NUDC1
NudC domain-containing protein 1

2

0

High-throughput

0.602

High

227052

PRKN
E3 ubiquitin-protein ligase parkin

2

8

High-throughput

0.584

High

902374

SAC1
Phosphatidylinositol-3-phosphatase SAC1

2

0

High-throughput

0.576

High

369303

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

902346

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

0

Small-scale

0.559

High

277683

PRAF3
PRA1 family protein 3

1

1

High-throughput

0.536

High

307014

RTN3
Reticulon-3

1

2

High-throughput

0.536

High

496722

TAU
Microtubule-associated protein tau

1

6

High-throughput

0.536

High

626088

APC
Adenomatous polyposis coli protein

1

2

High-throughput

0.536

High

902301

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.536

High

902320

ASTRB
Protein Aster-B

1

1

High-throughput

0.536

High

902324

UBR4
E3 ubiquitin-protein ligase UBR4

1

2

High-throughput

0.536

High

902329

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

1

High-throughput

0.536

High

902332

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

2

High-throughput

0.536

High

902352

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

1

High-throughput

0.536

High

902353

ASTRA
Protein Aster-A

1

1

High-throughput

0.536

High

902354

SCYL1
N-terminal kinase-like protein

1

2

High-throughput

0.536

High

902385

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

1

High-throughput

0.536

High

739052

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.513

High

825375

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.513

High

847429

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.513

High

902306

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

1

0

High-throughput

0.513

High

902342

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.513

High

902347

NU205
Nuclear pore complex protein Nup205

1

0

High-throughput

0.513

High

902357

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.513

High

902359

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.513

High

902365

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.513

High

902391

MYO5A
Unconventional myosin-Va

1

0

High-throughput

0.513

High

394465

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

729256

VGFR3
Vascular endothelial growth factor receptor 3

1

3

High-throughput

0.500

High

170830

PGRC2
Membrane-associated progesterone receptor component 2

1

1

High-throughput

0.489

High

452713

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

3

High-throughput

0.489

High

872628

EPHA4
Ephrin type-A receptor 4

1

4

High-throughput

0.489

High

902298

RBM10
RNA-binding protein 10

1

2

High-throughput

0.489

High

902315

SF3B4
Splicing factor 3B subunit 4

1

1

High-throughput

0.489

High

902341

ATLA2
Atlastin-2

1

3

High-throughput

0.489

High

162572

XPO1
Exportin-1

1

11

High-throughput

0.479

High

319782

HERC2
E3 ubiquitin-protein ligase HERC2

1

2

High-throughput

0.479

High

322416

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

505610

EPB41
Protein 4.1

1

2

High-throughput

0.479

High

874765

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

902292

ARF6
ADP-ribosylation factor 6

1

11

High-throughput

0.479

High

902305

CUL3
Cullin-3

1

1

High-throughput

0.479

High

902330

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

2

High-throughput

0.479

High

902343

BICD2
Protein bicaudal D homolog 2

1

1

High-throughput

0.479

High

902368

GLP3L
Golgi phosphoprotein 3-like

1

1

Small-scale

0.479

High

902369

GOLP3
Golgi phosphoprotein 3

1

1

Small-scale

0.479

High

902382

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

902384

FZR1
Fizzy-related protein homolog

1

1

High-throughput

0.479

High

902388

SHLB1
Endophilin-B1

1

1

High-throughput

0.479

High

324315

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

503815

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

684588

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

779150

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

902299

CDK5
Cyclin-dependent kinase 5

1

0

High-throughput

0.458

High

902317

SEPT7
Septin-7

1

0

High-throughput

0.458

High

902319

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

902350

CSN5
COP9 signalosome complex subunit 5

1

0

High-throughput

0.458

High

902351

FBXW7
F-box/WD repeat-containing protein 7

1

0

High-throughput

0.458

High

902371

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

902377

MKS1
Tectonic-like complex member MKS1

1

0

High-throughput

0.458

High

902386

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.458

High

902387

RRP44
Exosome complex exonuclease RRP44

1

0

High-throughput

0.458

High

445841

ROS1
Proto-oncogene tyrosine-protein kinase ROS

1

6

High-throughput

0.457

High

601490

FGFR2
Fibroblast growth factor receptor 2

1

6

High-throughput

0.457

High

665464

EPHA8
Ephrin type-A receptor 8

1

3

High-throughput

0.457

High

48315

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.445

High

258916

RTN2
Reticulon-2

1

2

High-throughput

0.445

High

277042

STAM2
Signal transducing adapter molecule 2

1

4

High-throughput

0.445

High

310584

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.445

High

501911

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.445

High

653543

CALR
Calreticulin

1

2

High-throughput

0.445

High

654232

CALX
Calnexin

1

2

High-throughput

0.445

High

787639

PI4KA
Phosphatidylinositol 4-kinase alpha

1

3

High-throughput

0.445

High

902293

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

4

High-throughput

0.445

High

902309

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.445

High

902313

TMED2
Transmembrane emp24 domain-containing protein 2

1

3

High-throughput

0.445

High

902323

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

3

High-throughput

0.445

High

902327

LCLT1
Lysocardiolipin acyltransferase 1

1

1

High-throughput

0.445

High

902336

DHB11
Estradiol 17-beta-dehydrogenase 11

1

3

High-throughput

0.445

High

902344

SCFD1
Sec1 family domain-containing protein 1

1

1

High-throughput

0.445

High

902345

ATLA1
Atlastin-1

1

3

High-throughput

0.445

High

902360

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.445

High

902367

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.445

High

902373

RTN4
Reticulon-4

1

2

High-throughput

0.445

High

902380

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.445

High

902389

DHRS7
Dehydrogenase/reductase SDR family member 7

1

2

High-throughput

0.445

High

902390

TMED5
Transmembrane emp24 domain-containing protein 5

1

3

High-throughput

0.445

High

552409

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.437

High

650857

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.437

High

659267

DUS1
Dual specificity protein phosphatase 1

1

7

High-throughput

0.437

High

720141

RFA3
Replication protein A 14 kDa subunit

1

3

High-throughput

0.437

High

902294

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

902303

DUS8
Dual specificity protein phosphatase 8

1

8

High-throughput

0.437

High

902304

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.437

High

902308

NOLC1
Nucleolar and coiled-body phosphoprotein 1

1

2

High-throughput

0.437

High

902318

E2F4
Transcription factor E2F4

1

2

High-throughput

0.437

High

902321

DUS28
Dual specificity phosphatase 28

1

8

High-throughput

0.437

High

902322

Q4LE69
1-phosphatidylinositol 4-kinase

1

3

High-throughput

0.437

High

902325

ATLA3
Atlastin-3

1

3

High-throughput

0.437

High

902326

SCYL2
SCY1-like protein 2

1

2

High-throughput

0.437

High

902328

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.437

High

902331

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.437

High

902348

ESR2
Estrogen receptor beta

1

3

High-throughput

0.437

High

902370

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

50125

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.426

High

58068

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.426

High

199316

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.426

High

200996

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.426

High

202858

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.426

High

266138

ERLN1
Erlin-1

1

0

High-throughput

0.426

High

335396

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.426

High

432625

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.426

High

821965

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.426

High

827776

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.426

High

902295

NUCB2
Nucleobindin-2

1

0

High-throughput

0.426

High

902302

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

902310

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.426

High

902311

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

902314

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.426

High

902316

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.426

High

902334

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.426

High

902335

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.426

High

902338

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.426

High

902340

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.426

High

902363

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

902364

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.426

High

902366

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

902379

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.426

High

902392

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

902362

TMED9
Transmembrane emp24 domain-containing protein 9

1

2

Small-scale

0.408

High

99781

F5H6I7
Atlastin GTPase 3

1

3

High-throughput

0.407

High

606983

UD11
UDP-glucuronosyltransferase 1A1

1

0

Small-scale

0.391

High

176162

PPM1G
Protein phosphatase 1G

1

0

High-throughput

0.279

Low

245804

CATL2
Cathepsin L2

1

0

High-throughput

0.279

Low

722203

RFC1
Replication factor C subunit 1

1

0

High-throughput

0.279

Low

885757

SIM11
Small integral membrane protein 11

1

0

High-throughput

0.279

Low

902312

RCN1
Reticulocalbin-1

1

0

High-throughput

0.279

Low

902333

TOM5
Mitochondrial import receptor subunit TOM5 homolog

1

0

High-throughput

0.279

Low

902337

SHCBP
SHC SH2 domain-binding protein 1

1

0

High-throughput

0.279

Low

902339

NAV1
Neuron navigator 1

1

0

High-throughput

0.279

Low

902355

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

0

High-throughput

0.279

Low

902372

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.279

Low

239552

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

569502

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

867170

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

0

High-throughput

0.249

Low

902296

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.249

Low

902349

PRCC
Proline-rich protein PRCC

1

0

High-throughput

0.249

Low

902383

CHRD1
Cysteine and histidine-rich domain-containing protein 1

1

0

High-throughput

0.249

Low

297738

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.232

Low

532095

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.232

Low

847242

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.232

Low

902300

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.232

Low

902307

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.232

Low

902358

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.232

Low

902361

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.232

Low

902375

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.232

Low

902376

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.232

Low

902378

PSD3
PH and SEC7 domain-containing protein 3

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024