Interactor 1: STK25 (O00506)
Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)
Gene: STK25

Interactor 2: PDC10 (Q9BUL8)
Programmed cell death protein 10 (Cerebral cavernous malformations 3 protein) (TF-1 cell apoptosis-related protein 15)
Gene: PDCD10

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 0.60 0.767

The method score is based on:

Property Details
Experiments 28514442, 32296183, 18782753, 33961781, 25416956, 26186194, 16189514, 21516116, 35271311, 32707033, 23455922, 23665169, 17657516, 31515488, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, x-ray crystallography, surface plasmon resonance, molecular sieving, pull down, cosedimentation in solution, two hybrid prey pooling approach, two hybrid array, validated two hybrid and 4 others

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Interaction Type physical association, direct interaction, phosphorylation reaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005794 - Golgi apparatus
GO:0032874 - positive regulation of stress-activated MAPK cascade
GO:0036481 - intrinsic apoptotic signaling pathway in response to hydrogen peroxide
GO:0042803 - protein homodimerization activity
and 3 others

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Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 426
Hs

1 212
+ Hs
+ Hs
+ Hs
+ Hs
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024