HitPredict

Interactor 1: PCGF6 (Q9BYE7)
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)
Gene: PCGF6

Interactor 2: CBX8 (Q9HC52)
Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1)
Gene: CBX8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.939

The method score is based on:

Property Details
Experiments 28514442, 33961781, 27705803, 24981860, 21282530
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CBX7_C~RAWUL
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0031519 - PcG protein complex
GO:0035102 - PRC1 complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 350
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024