HitPredict

Interactor 1: MK67I (Q9BYG3)
MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar phosphoprotein Nopp34) (Nucleolar protein interacting with the FHA domain of pKI-67) (hNIFK)
Gene: NIFK

Interactor 2: TOPRS (Q9NS56)
E3 ubiquitin-protein ligase Topors (EC 2.3.2.27) (RING-type E3 ubiquitin transferase Topors) (SUMO1-protein E3 ligase Topors) (Topoisomerase I-binding RING finger protein) (Topoisomerase I-binding arginine/serine-rich protein) (Tumor suppressor p53-binding protein 3) (p53-binding protein 3) (p53BP3)
Gene: TOPORS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 1045
+	Hs
		517817 MK67I_HUMAN (1-293): 8.07e-53: 176: 100.00		NFH_HUMAN (555-1030): 1.25e-10: 67.8: 9.43
+	Dm
		1187389 PUF68_DROME (47-118): 3.97e-10: 62.1: 34.72		Q7YZ99_DROME (399-989): 5.38e-11: 69: 10.62