HitPredict

Interactor 1: BCL9 (O00512)
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)
Gene: BCL9

Interactor 2: TLX1 (P31314)
T-cell leukemia homeobox protein 1 (Homeobox protein Hox-11) (Proto-oncogene TCL-3) (T-cell leukemia/lymphoma protein 3)
Gene: TLX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1426 Hs			1 330
+	Hs
		131679 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		TLX2_HUMAN (4-327): 2e-39: 142: 50.89
+	Hs
		131678 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94
+	Hs
		131708 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		GSC_HUMAN (58-285): 5.34e-30: 116: 20.61
+	Hs
		679182 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00
+	Hs
		679137 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00
+	Hs
		679200 NCOR2_HUMAN (2-1293): 5.66e-11: 69.8: 7.88		TLX1_HUMAN (1-330): 1.72e-60: 198: 100.00
+	Hs
		213398 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		TLX2_HUMAN (4-327): 2e-39: 142: 50.89
+	Hs
		967993 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		PO5F1_HUMAN (31-327): 1.93e-33: 128: 17.00
+	Hs
		211986 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94
+	Hs
		211903 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94
+	Hs
		213358 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		TLX2_HUMAN (4-327): 2e-39: 142: 50.89
+	Hs
		213412 NCOR2_HUMAN (2-1293): 5.66e-11: 69.8: 7.88		TLX2_HUMAN (4-327): 2e-39: 142: 50.89
+	Hs
		882140 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		GSC_HUMAN (58-285): 5.34e-30: 116: 20.61
+	Mm
		590420 KMT2C_MOUSE (355-1262): 5.74e-13: 76.6: 10.76		PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15
+	Hs
		211855 NCOA6_HUMAN (1-1013): 5.94e-12: 72.9: 7.69		TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94
+	Mm
		590489 ANR17_MOUSE (563-1132): 2.68e-11: 70.8: 9.34		PO5F1_MOUSE (32-327): 1.17e-33: 128: 15.15
+	Hs
		211919 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94
+	Hs
		212006 NCOR2_HUMAN (2-1293): 5.66e-11: 69.8: 7.88		TLX3_HUMAN (11-325): 9.96e-34: 127: 47.94
+	Hs
		882142 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		GSC_HUMAN (58-285): 5.34e-30: 116: 20.61
+	Hs
		882174 NCOR2_HUMAN (2-1293): 5.66e-11: 69.8: 7.88		GSC_HUMAN (58-285): 5.34e-30: 116: 20.61