Interactor 1: BCL9 (O00512)
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)
Gene: BCL9

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.926

The method score is based on:

Property Details
Experiments 24360964, 31073027, 34079125, 17052462, 11955446
Identification Methods affinity chromatography technology, proximity labelling technology, isothermal titration calorimetry, x-ray crystallography, pull down, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Arm~BCL9
Common GO terms GO:0003713 - transcription coactivator activity
GO:0005654 - nucleoplasm
GO:0006366 - transcription by RNA polymerase II
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0060070 - canonical Wnt signaling pathway
and 1 others

more...

Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1426
Hs

1 781
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024