HitPredict

Interactor 1: BCL9 (O00512)
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)
Gene: BCL9

Interactor 2: LHX1 (P48742)
LIM/homeobox protein Lhx1 (LIM homeobox protein 1) (Homeobox protein Lim-1) (hLim-1)
Gene: LHX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006366 - transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1426 Hs			1 406
+	Hs
		131749 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95
+	Hs
		131736 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49
+	Hs
		131710 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		ISL1_HUMAN (1-347): 4.01e-54: 184: 27.35
+	Hs
		131704 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX2_HUMAN (2-317): 3.11e-51: 178: 26.84
+	Hs
		131737 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		ISL2_HUMAN (4-346): 8.63e-46: 163: 28.53
+	Hs
		131726 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX8_HUMAN (3-307): 2.36e-45: 162: 27.36
+	Hs
		131751 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX6_HUMAN (2-259): 1.04e-44: 160: 30.77
+	Hs
		822688 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX1_HUMAN (1-406): 1.12e-95: 293: 100.00
+	Hs
		822650 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		LHX1_HUMAN (1-406): 1.12e-95: 293: 100.00
+	Hs
		1350240 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95
+	Hs
		1281194 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49
+	Hs
		1200125 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49
+	Hs
		839836 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX2_HUMAN (2-317): 3.11e-51: 178: 26.84
+	Hs
		899924 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		ISL1_HUMAN (1-347): 4.01e-54: 184: 27.35
+	Hs
		1243849 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		LHX3_HUMAN (1-374): 4.86e-60: 201: 33.95
+	Hs
		839774 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		LHX2_HUMAN (2-317): 3.11e-51: 178: 26.84
+	Hs
		1243832 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		LHX4_HUMAN (1-398): 3.46e-58: 196: 31.49
+	Hs
		1200126 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		ISL2_HUMAN (4-346): 8.63e-46: 163: 28.53
+	Hs
		1200133 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		LHX6_HUMAN (2-259): 1.04e-44: 160: 30.77
+	Hs
		839785 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		LHX2_HUMAN (2-317): 3.11e-51: 178: 26.84