Protein: SRP68
Signal recognition particle subunit SRP68 (Signal recognition particle 68 kDa protein homolog)

Gene: SRP68
Organism: Saccharomyces cerevisiae S288C
Interactions: 62
UniProt ID: P38687

Gene Ontology (top 5):
GO:0005047 - signal recognition particle binding
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
GO:0005786 - signal recognition particle, endoplasmic reticulum targeting
GO:0006614 - SRP-dependent cotranslational protein targeting to membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

592892

SRP54
Signal recognition particle subunit SRP54

3

2

High-throughput

0.855

High

667815

SEC65
Signal recognition particle subunit SEC65

5

1

Small-scale

0.709

High

752007

SRP72
Signal recognition particle subunit SRP72

5

2

Small-scale

0.706

High

704883

LHP1
La protein homolog

3

3

High-throughput

0.667

High

752009

SRP14
Signal recognition particle subunit SRP14

4

0

High-throughput

0.661

High

688082

SRP21
Signal recognition particle subunit SRP21

2

0

High-throughput

0.576

High

676017

XPO1
Exportin-1

1

4

High-throughput

0.536

High

752019

BRE5
UBP3-associated protein BRE5

1

1

High-throughput

0.536

High

752021

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

2

High-throughput

0.536

High

752032

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.513

High

404566

RL7A
Large ribosomal subunit protein uL30A

1

1

High-throughput

0.479

High

407019

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

407888

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

480077

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

534970

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

624074

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.479

High

638738

SPB4
ATP-dependent rRNA helicase SPB4

1

2

High-throughput

0.479

High

640927

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.479

High

729883

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

742768

GBLP
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.479

High

752017

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

752023

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.479

High

141302

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.458

High

524280

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

664803

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

698787

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

752008

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.458

High

752029

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

368014

EF1A
Elongation factor 1-alpha

1

2

High-throughput

0.445

High

491092

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

493862

HSP72
Heat shock protein SSA2

1

2

High-throughput

0.445

High

511166

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.445

High

694616

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

752012

IMB4
Importin subunit beta-4

1

1

High-throughput

0.445

High

752013

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

383117

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.437

High

480644

RS8A
Small ribosomal subunit protein eS8A

1

1

High-throughput

0.437

High

700381

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

752014

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.437

High

752031

RLM1
Transcription factor RLM1

1

1

High-throughput

0.437

High

424494

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

628968

SCJ1
DnaJ-related protein SCJ1

1

0

High-throughput

0.426

High

705128

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

752015

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.426

High

752020

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

707845

GCN1
eIF-2-alpha kinase activator GCN1

1

2

High-throughput

0.407

High

752026

RPN9
26S proteasome regulatory subunit RPN9

1

1

High-throughput

0.407

High

752028

CDC73
Cell division control protein 73

1

0

High-throughput

0.269

Low

635041

RDS1
Regulator of drug sensitivity 1

1

0

High-throughput

0.265

Low

628002

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

662114

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

688753

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.249

Low

701412

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

752011

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

752018

UBC9
SUMO-conjugating enzyme UBC9

1

0

High-throughput

0.249

Low

752025

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

752027

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

752030

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

752022

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

752010

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.232

Low

752016

ALDH4
Potassium-activated aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.232

Low

752024

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024