Protein: XRCC6
X-ray repair cross-complementing protein 6 (EC 3.6.4.-) (EC 4.2.99.-) (5'-deoxyribose-5-phosphate lyase Ku70) (5'-dRP/AP lyase Ku70) (ATP-dependent DNA helicase 2 subunit 1) (ATP-dependent DNA helicase II 70 kDa subunit) (CTC box-binding factor 75 kDa subunit) (CTC75) (CTCBF) (DNA repair protein XRCC6) (Ku autoantigen protein p70 homolog) (Ku70)

Gene: XRCC6
Organism: Mus musculus
Interactions: 22
UniProt ID: P23475

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000725 - recombinational repair
GO:0003684 - damaged DNA binding
GO:0003678 - DNA helicase activity
GO:0003690 - double-stranded DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

629183

PO5F1
POU domain, class 5, transcription factor 1

1

8

High-throughput

0.536

High

659099

TF2L1
Transcription factor CP2-like protein 1

1

4

High-throughput

0.536

High

659105

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

6

High-throughput

0.536

High

659106

MYOME
Myomegalin

1

2

High-throughput

0.536

High

312337

FOXL2
Forkhead box protein L2

1

1

Small-scale

0.481

High

147709

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

High-throughput

0.479

High

644242

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

1

2

Small-scale

0.479

High

659095

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

659096

CDX2
Homeobox protein CDX-2

1

8

High-throughput

0.479

High

659097

SOX2
Transcription factor SOX-2

1

10

High-throughput

0.479

High

659098

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C]

1

2

Small-scale

0.479

High

659100

CLU
Clustered mitochondria protein homolog

1

2

High-throughput

0.479

High

659101

ERR2
Steroid hormone receptor ERR2

1

13

High-throughput

0.479

High

659102

TFE3
Transcription factor E3

1

5

High-throughput

0.479

High

659103

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

5

High-throughput

0.479

High

659108

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.479

High

659109

TRI29
Tripartite motif-containing protein 29

1

4

Small-scale

0.479

High

508957

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

3

High-throughput

0.457

High

659107

HMBX1
Homeobox-containing protein 1

1

4

Small-scale

0.445

High

408204

IL2
Interleukin-2

1

3

Small-scale

0.437

High

312693

LMX1B
LIM homeobox transcription factor 1-beta

1

0

Small-scale

0.426

High

659104

PARP6
Protein mono-ADP-ribosyltransferase PARP6

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025