Protein: FKS1
1,3-beta-glucan synthase component FKS1 (EC 2.4.1.34) (1,3-beta-D-glucan-UDP glucosyltransferase) (Calcineurin dependent protein 1) (Calcofluor white hypersensitivity protein 53) (Echinocandin target gene protein 1) (FK506 sensitivity protein 1) (Glucan synthase of cerevisiae protein 1) (Papulacandin B resistance protein 1)

Gene: FKS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 173
UniProt ID: P38631

Gene Ontology (top 5):
GO:0000148 - 1,3-beta-D-glucan synthase complex
GO:0003843 - 1,3-beta-D-glucan synthase activity
GO:0005739 - mitochondrion
GO:0005886 - plasma membrane
GO:0005933 - cellular bud

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

419690

RHO1
GTP-binding protein RHO1

2

0

Small-scale

0.601

High

751362

FLC2
Flavin carrier protein 2

2

2

High-throughput

0.588

High

751383

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

680669

HS104
Heat shock protein 104

3

1

High-throughput

0.578

High

748226

FTH1
Iron transporter FTH1

2

0

High-throughput

0.563

High

751369

SCS2
Vesicle-associated membrane protein-associated protein SCS2

2

0

High-throughput

0.563

High

491088

HSP71
Heat shock protein SSA1

2

4

High-throughput

0.552

High

700235

PMP1
Plasma membrane ATPase proteolipid 1

2

0

High-throughput

0.547

High

747312

PHO88
SRP-independent targeting protein 3

2

0

High-throughput

0.547

High

530078

ATC1
Calcium-transporting ATPase 1

1

1

High-throughput

0.536

High

562710

FUS3
Mitogen-activated protein kinase FUS3

1

1

High-throughput

0.536

High

625972

PTP1
Tyrosine-protein phosphatase 1

1

1

High-throughput

0.536

High

751364

RSP5
E3 ubiquitin-protein ligase RSP5

1

2

High-throughput

0.536

High

751373

PRK1
Actin-regulating kinase PRK1

1

1

High-throughput

0.536

High

751390

CLA4
Serine/threonine-protein kinase CLA4

1

1

High-throughput

0.536

High

751406

ARK1
Actin-regulating kinase 1

1

1

High-throughput

0.536

High

580818

GAP1
General amino-acid permease GAP1

1

0

Small-scale

0.529

High

700380

RSSA1
Small ribosomal subunit protein uS2A

2

1

High-throughput

0.521

High

751210

NCB5R
NADH-cytochrome b5 reductase 1

1

1

High-throughput

0.515

High

526225

KIN2
Serine/threonine-protein kinase KIN2

1

0

High-throughput

0.513

High

751365

BEM2
GTPase-activating protein BEM2/IPL2

1

0

High-throughput

0.513

High

751393

PHB2
Prohibitin-2

1

0

High-throughput

0.513

High

539246

YAK1
Dual specificity protein kinase YAK1

1

1

High-throughput

0.489

High

605638

KIN3
Serine/threonine-protein kinase KIN3

1

3

High-throughput

0.489

High

743138

BOB1
Protein BOB1

1

1

Small-scale

0.481

High

751366

BOI2
Protein BOI2

1

1

Small-scale

0.481

High

751443

AIM44
Altered inheritance of mitochondria protein 44

1

0

Small-scale

0.479

High

357270

RMAR
Small ribosomal subunit protein uS3m

1

1

High-throughput

0.479

High

425621

KAPR
cAMP-dependent protein kinase regulatory subunit

1

1

Small-scale

0.479

High

522416

STE6
Alpha-factor-transporting ATPase

1

1

High-throughput

0.479

High

667386

CHS3
Chitin synthase 3

1

2

High-throughput

0.479

High

678150

SNC1
Synaptobrevin homolog 1

1

2

High-throughput

0.479

High

697474

ATC5
Phospholipid-transporting ATPase DNF1

1

1

High-throughput

0.479

High

699489

SSO1
Protein SSO1

1

1

High-throughput

0.479

High

704511

SNC2
Synaptobrevin homolog 2

1

2

High-throughput

0.479

High

751378

FKS2
1,3-beta-glucan synthase component GSC2

1

1

High-throughput

0.479

High

751381

LEM3
Phospholipid-transporting ATPase accessory subunit LEM3

1

2

High-throughput

0.479

High

751416

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.479

High

751418

YM8V
Uncharacterized protein YMR295C

1

1

High-throughput

0.479

High

751429

SSP2
Sporulation-specific protein 2

1

1

Small-scale

0.479

High

751432

FLC1
Flavin carrier protein 1

1

2

High-throughput

0.479

High

751440

ATC4
Phospholipid-transporting ATPase DNF2

1

1

High-throughput

0.479

High

666253

BEM1
Bud emergence protein 1

1

0

Small-scale

0.460

High

606265

VPS15
Serine/threonine-protein kinase VPS15

1

0

High-throughput

0.458

High

635289

SYP1
Suppressor of yeast profilin deletion

1

0

Small-scale

0.458

High

647447

AP2B
AP-2 complex subunit beta

1

0

Small-scale

0.458

High

664447

HRR25
Casein kinase I homolog HRR25

1

0

Small-scale

0.458

High

751360

PHO90
Low-affinity phosphate transporter PHO90

1

0

High-throughput

0.458

High

751363

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

High-throughput

0.458

High

751380

MMM1
Maintenance of mitochondrial morphology protein 1

1

0

Small-scale

0.458

High

751382

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.458

High

751385

ATG27
Autophagy-related protein 27

1

0

High-throughput

0.458

High

751396

MDM34
Mitochondrial distribution and morphology protein 34

1

0

Small-scale

0.458

High

751398

AIM14
Probable metalloreductase AIM14

1

0

High-throughput

0.458

High

751400

TNA1
High-affinity nicotinic acid transporter

1

0

High-throughput

0.458

High

751404

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

751405

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

751414

ESP1
Separin

1

0

High-throughput

0.458

High

751419

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

751421

SEC13
Protein transport protein SEC13

1

0

High-throughput

0.458

High

751434

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.458

High

477256

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

1

High-throughput

0.457

High

366223

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.445

High

493856

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

535984

CHS2
Chitin synthase 2

1

2

High-throughput

0.445

High

693397

SMI1
Cell wall assembly regulator SMI1

1

1

High-throughput

0.445

High

751358

YM11
Uncharacterized protein YMR124W

1

1

High-throughput

0.445

High

751412

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

1

1

High-throughput

0.445

High

751394

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

1

Small-scale

0.439

High

546727

SEC23
Protein transport protein SEC23

1

1

High-throughput

0.437

High

660327

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.437

High

662112

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

730789

CENPA
Histone H3-like centromeric protein CSE4

1

3

High-throughput

0.437

High

751354

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

751359

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

751372

SEC24
Protein transport protein SEC24

1

1

High-throughput

0.437

High

751386

MPS3
Spindle pole body assembly component MPS3

1

1

High-throughput

0.437

High

751392

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

751401

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.437

High

751409

H3
Histone H3

1

3

High-throughput

0.437

High

751417

VPS60
Vacuolar protein-sorting-associated protein 60

1

1

Small-scale

0.437

High

751438

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.437

High

689082

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.426

High

698310

COX13
Cytochrome c oxidase subunit 13, mitochondrial

1

0

High-throughput

0.426

High

699094

YME2
Mitochondrial escape protein 2

1

0

High-throughput

0.426

High

731651

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

High-throughput

0.426

High

751368

PIC2
Mitochondrial phosphate carrier protein 2

1

0

High-throughput

0.426

High

751370

COX15
Heme A synthase COX15

1

0

High-throughput

0.426

High

751375

SNL1
HSP70 co-chaperone SNL1

1

0

High-throughput

0.426

High

751395

ERG25
C-4 methylsterol oxidase ERG25

1

0

High-throughput

0.426

High

751399

YG1I
Uncharacterized membrane protein YGR026W

1

0

High-throughput

0.426

High

751426

CRD1
Cardiolipin synthase

1

0

High-throughput

0.426

High

751433

FSF1
Sideroflexin FSF1

1

0

High-throughput

0.426

High

751435

NCE2
Non-classical export protein 2

1

0

High-throughput

0.426

High

751442

YB111
Uncharacterized helicase-like protein YBL111C

1

0

High-throughput

0.426

High

743515

HMT1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.417

High

751403

PFD4
Prefoldin subunit 4

1

1

High-throughput

0.407

High

751361

ERP2
Protein ERP2

3

0

High-throughput

0.339

High

733730

BET3
Trafficking protein particle complex subunit BET3

2

0

High-throughput

0.328

High

502990

SEC7
Protein transport protein SEC7

2

0

High-throughput

0.324

High

601693

SEC62
Translocation protein SEC62

2

0

High-throughput

0.324

High

748765

TRS20
Trafficking protein particle complex subunit 20

2

0

High-throughput

0.324

High

751415

ERO1
Endoplasmic oxidoreductin-1

2

0

High-throughput

0.324

High

576174

SPO7
Sporulation-specific protein SPO7

2

0

High-throughput

0.307

High

751377

LCB2
Serine palmitoyltransferase 2

2

0

High-throughput

0.307

High

524279

CAF20
Cap-associated protein CAF20

2

0

High-throughput

0.305

High

452536

KEX1
Pheromone-processing carboxypeptidase KEX1

2

0

High-throughput

0.298

High

602669

MCK1
Protein kinase MCK1

1

0

High-throughput

0.279

Low

697140

ANP1
Mannan polymerase II complex ANP1 subunit

1

0

High-throughput

0.279

Low

751388

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

0

High-throughput

0.279

Low

751422

ERV41
ER-derived vesicles protein ERV41

1

0

High-throughput

0.279

Low

751384

SPC1
Signal peptidase complex subunit 1

1

0

High-throughput

0.269

Low

141301

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

383116

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.249

Low

405595

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

407887

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

471028

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

472165

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

480076

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

606630

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

608955

VPS34
Phosphatidylinositol 3-kinase VPS34

1

0

High-throughput

0.249

Low

619460

PSA2
Proteasome subunit alpha type-2

1

0

High-throughput

0.249

Low

627999

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

635701

TAH1
TPR repeat-containing protein associated with Hsp90

1

0

Small-scale

0.249

Low

645415

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

691037

HOG1
Mitogen-activated protein kinase HOG1

1

0

High-throughput

0.249

Low

691993

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

1

0

High-throughput

0.249

Low

699300

PTM1
Membrane protein PTM1

1

0

High-throughput

0.249

Low

729882

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

731567

EAP1
Protein EAP1

1

0

High-throughput

0.249

Low

732279

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

0

High-throughput

0.249

Low

741288

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

0

High-throughput

0.249

Low

742767

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.249

Low

745977

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.249

Low

747573

ATG14
Autophagy-related protein 14

1

0

High-throughput

0.249

Low

748129

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

751355

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.249

Low

751356

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

751376

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

751391

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

751397

ATG1
Serine/threonine-protein kinase ATG1

1

0

High-throughput

0.249

Low

751402

ATG2
Autophagy-related protein 2

1

0

High-throughput

0.249

Low

751411

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

751413

BECN1
Vacuolar protein sorting-associated protein 30

1

0

High-throughput

0.249

Low

751420

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.249

Low

751423

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

751424

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.249

Low

751425

ATG23
Autophagy-related protein 23

1

0

High-throughput

0.249

Low

751427

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

751428

MCA1
Metacaspase-1

1

0

High-throughput

0.249

Low

751430

ESA1
Histone acetyltransferase ESA1

1

0

Small-scale

0.249

Low

751431

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

751436

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.249

Low

751439

ATG11
Autophagy-related protein 11

1

0

High-throughput

0.249

Low

751444

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low

567582

PHO81
Phosphate system positive regulatory protein PHO81

1

0

High-throughput

0.232

Low

605895

SLY41
Uncharacterized transporter SLY41

1

0

High-throughput

0.232

Low

660282

SEC20
Protein transport protein SEC20

1

0

High-throughput

0.232

Low

728025

YET1
Endoplasmic reticulum transmembrane protein 1

1

0

High-throughput

0.232

Low

732412

STB6
Protein STB6

1

0

High-throughput

0.232

Low

747779

MKAR
Very-long-chain 3-oxoacyl-CoA reductase

1

0

High-throughput

0.232

Low

751357

AKR1
Palmitoyltransferase AKR1

1

0

High-throughput

0.232

Low

751367

NUG1
Nuclear GTP-binding protein NUG1

1

0

High-throughput

0.232

Low

751371

ELO3
Fatty acid elongase 3

1

0

High-throughput

0.232

Low

751374

ICE2
Protein ICE2

1

0

High-throughput

0.232

Low

751379

SYS1
Protein SYS1

1

0

High-throughput

0.232

Low

751387

NOP9
Nucleolar protein 9

1

0

High-throughput

0.232

Low

751389

SEC16
COPII coat assembly protein SEC16

1

0

High-throughput

0.232

Low

751407

TMEDA
Endoplasmic reticulum vesicle protein 25

1

0

High-throughput

0.232

Low

751408

SNA2
Protein SNA2

1

0

High-throughput

0.232

Low

751410

PEX13
Peroxisomal membrane protein PEX13

1

0

High-throughput

0.232

Low

751437

MAM3
Protein MAM3

1

0

High-throughput

0.232

Low

751441

RRP12
Ribosomal RNA-processing protein 12

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024