HitPredict

Interactor 1: LAD1 (O00515)
Ladinin-1 (Lad-1) (Linear IgA disease antigen) (LADA)
Gene: LAD1

Interactor 2: FLNB (O75369)
Filamin-B (FLN-B) (ABP-278) (ABP-280 homolog) (Actin-binding-like protein) (Beta-filamin) (Filamin homolog 1) (Fh1) (Filamin-3) (Thyroid autoantigen) (Truncated actin-binding protein) (Truncated ABP)
Gene: FLNB

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015629 - actin cytoskeleton GO:0045296 - cadherin binding GO:0070062 - extracellular exosome
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 517 Hs			1 2602
+	Hs
		261264 MDC1_HUMAN (2-510): 5.59e-13: 73.9: 10.82		FLNB_HUMAN (1-2602): 0: 2855: 100.00
+	Hs
		131766 LAD1_HUMAN (1-517): 2.58e-69: 232: 100.00		FLNA_HUMAN (1-2602): 0: 2661: 69.59
+	Hs
		598120 MDC1_HUMAN (2-510): 5.59e-13: 73.9: 10.82		FLNA_HUMAN (1-2602): 0: 2661: 69.59
+	Hs
		598171 NIPBL_HUMAN (39-512): 1.39e-11: 69.5: 14.35		FLNA_HUMAN (1-2602): 0: 2661: 69.59
+	Hs
		598253 TITIN_HUMAN (22-477): 8.04e-09: 60.8: 10.75		FLNA_HUMAN (1-2602): 0: 2661: 69.59
+	Hs
		131777 LAD1_HUMAN (1-517): 2.58e-69: 232: 100.00		FLNC_HUMAN (6-2602): 0: 1470: 35.38
+	Hs
		993278 TITIN_HUMAN (22-477): 8.04e-09: 60.8: 10.75		ACTN3_HUMAN (5-364): 1.21e-118: 402: 26.88
+	Hs
		521586 TITIN_HUMAN (22-477): 8.04e-09: 60.8: 10.75		ACTN1_HUMAN (5-364): 3.89e-117: 397: 27.15
+	Hs
		725681 TITIN_HUMAN (22-477): 8.04e-09: 60.8: 10.75		ACTN2_HUMAN (5-364): 2.6e-116: 395: 26.61
+	Hs
		211629 TITIN_HUMAN (22-477): 8.04e-09: 60.8: 10.75		ACTN4_HUMAN (12-364): 9.99e-114: 388: 26.58
+	Dm
		65342 OBSCN_DROME (197-490): 4.91e-10: 64.6: 12.59		Q9W4Y3_DROME (1136-2158): 3.74e-24: 114: 10.66