Interactor 1: KRIT1 (O00522)
Krev interaction trapped protein 1 (Krev interaction trapped 1) (Cerebral cavernous malformations 1 protein)
Gene: KRIT1

Interactor 2: TIAM1 (Q13009)
Rho guanine nucleotide exchange factor TIAM1 (T-lymphoma invasion and metastasis-inducing protein 1) (TIAM-1)
Gene: TIAM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 0.60 0.541

The method score is based on:

Property Details
Experiments 35914814
Identification Methods two hybrid, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0007264 - small GTPase-mediated signal transduction
GO:0008017 - microtubule binding
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 736
Hs

1 1591
+ Hs
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024