HitPredict

Interactor 1: TRIM5 (Q9C035)
Tripartite motif-containing protein 5 (EC 2.3.2.27) (RING finger protein 88) (RING-type E3 ubiquitin transferase TRIM5)
Gene: TRIM5

Interactor 2: TRI35 (Q9UPQ4)
E3 ubiquitin-protein ligase TRIM35 (EC 2.3.2.27) (Hemopoietic lineage switch protein 5)
Gene: TRIM35

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 16775307
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PRY~SPRY, SPRY~SPRY, zf-B_box~zf-B_box, zf-B_box~zf-RING_UBOX, zf-RING_UBOX~zf-RING_UBOX
Common GO terms GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0044790 - suppression of viral release by host
GO:0045087 - innate immune response
GO:0061630 - ubiquitin protein ligase activity
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 493
Hs

1 493
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024