HitPredict

Interactor 1: VAMP5 (O95183)
Vesicle-associated membrane protein 5 (VAMP-5) (Myobrevin)
Gene: VAMP5

Interactor 2: SNP25 (P60880)
Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein)
Gene: SNAP25

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	30833792
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 116 Hs			1 206
+	Dm
		739423 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		SNP25_DROME (4-204): 2.89e-62: 194: 60.89
+	Hs
		117941 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		SNP23_HUMAN (12-205): 2.99e-59: 186: 59.51
+	Hs
		66336 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		A8K287_HUMAN (12-205): 2.99e-59: 186: 59.51
+	Dm
		1178123 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		Q9VH76_DROME (3-205): 1.5e-59: 187: 58.65
+	Dm
		577212 SYB_DROME (2-88): 9.74e-30: 105: 39.08		SNP25_DROME (4-204): 2.89e-62: 194: 60.89
+	Hs
		850549 VAMP7_HUMAN (4-96): 5.88e-26: 98: 31.18		SNP25_HUMAN (1-206): 1.77e-64: 199: 100.00
+	Rn
		893316 VAMP7_RAT (4-96): 7.13e-26: 98: 30.11		SNP25_RAT (1-206): 1.77e-64: 199: 100.00
+	Rn
		893314 VAMP1_RAT (2-78): 9.26e-27: 97.3: 37.66		SNP25_RAT (1-206): 1.77e-64: 199: 100.00
+	At
		1351793 VA721_ARATH (5-92): 9.82e-32: 113: 26.14		SNP33_ARATH (9-204): 6.59e-57: 183: 27.67
+	Hs
		620261 VAMP1_HUMAN (2-78): 6.73e-26: 95: 36.36		SNP25_HUMAN (1-206): 1.77e-64: 199: 100.00
+	At
		812701 VA722_ARATH (5-92): 1.2e-30: 110: 25.00		SNP33_ARATH (9-204): 6.59e-57: 183: 27.67
+	Hs
		306744 VAMP5_HUMAN (1-116): 2.4e-35: 118: 100.00		SNP29_HUMAN (3-202): 6.08e-54: 174: 20.44
+	Dm
		577245 SYB_DROME (2-88): 9.74e-30: 105: 39.08		Q9VH76_DROME (3-205): 1.5e-59: 187: 58.65
+	Hs
		117995 VAMP7_HUMAN (4-96): 5.88e-26: 98: 31.18		SNP23_HUMAN (12-205): 2.99e-59: 186: 59.51
+	Hs
		117935 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		SNP23_HUMAN (12-205): 2.99e-59: 186: 59.51
+	Hs
		320281 VAMP7_HUMAN (4-96): 5.88e-26: 98: 31.18		SNP29_HUMAN (3-202): 6.08e-54: 174: 20.44
+	Hs
		261624 VAMP4_HUMAN (3-73): 1.13e-25: 95.3: 29.58		SNP29_HUMAN (3-202): 6.08e-54: 174: 20.44
+	Hs
		320265 VAMP1_HUMAN (2-78): 6.73e-26: 95: 36.36		SNP29_HUMAN (3-202): 6.08e-54: 174: 20.44
+	Dm
		1178141 Q7JYX5_DROME (4-96): 1.36e-32: 114: 31.18		Q9W1I8_DROME (2-204): 4.73e-45: 152: 20.80
+	Dm
		577265 SYB_DROME (2-88): 9.74e-30: 105: 39.08		Q9W1I8_DROME (2-204): 4.73e-45: 152: 20.80