Interactor 1: TRIM9 (Q9C026)
E3 ubiquitin-protein ligase TRIM9 (EC 2.3.2.27) (RING finger protein 91) (RING-type E3 ubiquitin transferase TRIM9) (Tripartite motif-containing protein 9)
Gene: TRIM9

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 25190485, 32296183, 25332235, 25416956, 25900982, 16189514, 26091241, 28514442, 26871637, 33961781, unassigned1304, 31515488
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, validated two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, two hybrid pooling approach
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~fn3
Common GO terms GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0061630 - ubiquitin protein ligase activity
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 710
Hs

1 605
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Last updated: 15 Jul 2024