HitPredict

Interactor 1: TOLIP (Q9H0E2)
Toll-interacting protein
Gene: TOLLIP

Interactor 2: GGA2 (Q9UJY4)
ADP-ribosylation factor-binding protein GGA2 (Gamma-adaptin-related protein 2) (Golgi-localized, gamma ear-containing, ARF-binding protein 2) (VHS domain and ear domain of gamma-adaptin) (Vear)
Gene: GGA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15047686
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043130 - ubiquitin binding
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 274 Hs			1 613
+	Hs
		1327604 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		GGA1_HUMAN (19-612): 1.68e-159: 473: 44.67
+	Hs
		241171 Q6FIE9_HUMAN (1-274): 6.84e-178: 492: 100.00		TOM1_HUMAN (23-495): 1.66e-100: 316: 19.02
+	Hs
		241195 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		TOM1_HUMAN (23-495): 1.66e-100: 316: 19.02
+	Hs
		1270615 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		STAM1_HUMAN (19-524): 3.22e-96: 306: 15.76
+	Hs
		1173027 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		TM1L2_HUMAN (23-447): 3.99e-92: 295: 21.75
+	Rn
		58593 TOLIP_RAT (1-273): 9.9e-166: 461: 93.41		Q5XI21_RAT (23-496): 2.3e-101: 318: 19.05
+	Mm
		292211 TOLIP_MOUSE (1-273): 2.66e-165: 460: 93.04		TOM1_MOUSE (23-496): 7.57e-100: 314: 19.80
+	Hs
		272820 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		TM1L1_HUMAN (23-494): 3.31e-86: 278: 18.01
+	Hs
		1327594 TOLIP_HUMAN (1-274): 6.84e-178: 492: 100.00		GGA3_HUMAN (328-611): 1.6e-47: 179: 32.33