HitPredict

Interactor 1: KLH25 (Q9H0H3)
Kelch-like protein 25 (Ectoderm-neural cortex protein 2) (ENC-2)
Gene: KLHL25

Interactor 2: FXL17 (Q9UF56)
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)
Gene: FBXL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	30190310
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BTB~LRR_6
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 589 Hs			1 701
+	Hs
		1354642 KLH20_HUMAN (22-584): 6.39e-168: 492: 31.63		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		152501 ENC1_HUMAN (1-589): 4.51e-167: 490: 74.70		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1120825 KLH12_HUMAN (26-586): 1.62e-159: 470: 28.87		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1153798 KLH10_HUMAN (34-585): 4.48e-148: 441: 26.61		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1239687 KLH23_HUMAN (20-575): 5.86e-80: 263: 29.43		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354639 KLH21_HUMAN (18-572): 1e-71: 243: 31.22		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1049349 KEAP1_HUMAN (386-589): 1.24e-48: 180: 23.56		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		307226 KLHL2_HUMAN (390-589): 8.24e-45: 169: 27.59		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354637 KLHL3_HUMAN (440-589): 3.66e-35: 141: 23.18		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1348054 KLH28_HUMAN (430-589): 2.37e-34: 139: 18.86		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1164633 KLH24_HUMAN (373-588): 1.38e-29: 125: 20.18		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1164601 KLH17_HUMAN (480-589): 1.65e-19: 94.5: 27.03		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1354646 IPP_HUMAN (493-589): 1.49e-19: 94.5: 16.98		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1350481 KLH13_HUMAN (505-589): 6.85e-15: 79.8: 22.22		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00
+	Hs
		1350369 KLHL9_HUMAN (505-589): 1.78e-14: 78.7: 23.33		FXL17_HUMAN (1-701): 6.07e-166: 494: 100.00