Protein: GATA2
Endothelial transcription factor GATA-2 (GATA-binding protein 2)

Gene: GATA2
Organism: Homo sapiens
Interactions: 193
UniProt ID: P23769

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001221 - transcription coregulator binding
GO:0001223 - transcription coactivator binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

620346

FHL3
Four and a half LIM domains protein 3

2

1

High-throughput

0.811

High

620298

RBTN2
Rhombotin-2

1

11

Small-scale

0.740

High

572538

SPI1
Transcription factor PU.1

3

14

Small-scale

0.690

High

620382

FOG1
Zinc finger protein ZFPM1

3

11

Small-scale

0.667

High

620343

SMAD4
Mothers against decapentaplegic homolog 4

2

8

High-throughput

0.656

High

620299

PIT1
Pituitary-specific positive transcription factor 1

2

8

Small-scale

0.646

High

596029

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

2

2

High-throughput

0.628

High

620297

PSA3
Proteasome subunit alpha type-3

2

2

High-throughput

0.628

High

620306

TRI23
E3 ubiquitin-protein ligase TRIM23

2

1

High-throughput

0.628

High

620413

MDFI
MyoD family inhibitor

2

1

High-throughput

0.628

High

620294

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

13

High-throughput

0.618

High

620437

TRPS1
Zinc finger transcription factor Trps1

1

15

High-throughput

0.618

High

620305

MSX2
Homeobox protein MSX-2

2

13

High-throughput

0.606

High

620402

RBPMS
RNA-binding protein with multiple splicing

2

1

High-throughput

0.606

High

620310

TPC10
Trafficking protein particle complex subunit 10

2

0

High-throughput

0.602

High

620410

TPPC9
Trafficking protein particle complex subunit 9

2

0

High-throughput

0.602

High

620445

TPPC4
Trafficking protein particle complex subunit 4

2

0

High-throughput

0.602

High

620373

NT2NA
Notch homolog 2 N-terminal-like protein A

2

0

High-throughput

0.601

High

620338

EP300
Histone acetyltransferase p300

2

20

Small-scale

0.595

High

620398

CBP
CREB-binding protein

2

20

Small-scale

0.595

High

620324

SKP1
S-phase kinase-associated protein 1

2

1

Small-scale

0.584

High

135076

NFIB
Nuclear factor 1 B-type

1

9

High-throughput

0.578

High

443129

NFIC
Nuclear factor 1 C-type

1

10

High-throughput

0.578

High

620340

NFIA
Nuclear factor 1 A-type

1

11

High-throughput

0.578

High

620447

ZBT32
Zinc finger and BTB domain-containing protein 32

2

2

Small-scale

0.576

High

620302

PML
Protein PML

1

7

Small-scale

0.573

High

620336

GOGA2
Golgin subfamily A member 2

2

1

High-throughput

0.573

High

620342

TRAF1
TNF receptor-associated factor 1

1

1

High-throughput

0.573

High

620303

AKT1
RAC-alpha serine/threonine-protein kinase

1

2

Small-scale

0.569

High

620333

ZBT16
Zinc finger and BTB domain-containing protein 16

1

1

Small-scale

0.561

High

620353

MED1
Mediator of RNA polymerase II transcription subunit 1

1

9

Small-scale

0.561

High

620388

COP1
E3 ubiquitin-protein ligase COP1

1

8

Small-scale

0.561

High

620404

FBXW7
F-box/WD repeat-containing protein 7

1

6

Small-scale

0.561

High

66983

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.553

High

620360

KR133
Keratin-associated protein 13-3

2

1

High-throughput

0.553

High

620418

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

620332

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

2

High-throughput

0.536

High

620318

KR109
Keratin-associated protein 10-9

1

6

High-throughput

0.523

High

620356

OBF1
POU domain class 2-associating factor 1

1

0

High-throughput

0.518

High

620320

SMD3
Small nuclear ribonucleoprotein Sm D3

1

2

High-throughput

0.515

High

281546

WFS1
Wolframin

1

1

High-throughput

0.515

High

620300

CLAT
Choline O-acetyltransferase

1

1

High-throughput

0.515

High

620301

GRN
Progranulin

1

1

High-throughput

0.515

High

620448

RNF11
RING finger protein 11

1

1

High-throughput

0.515

High

568177

TAL1
T-cell acute lymphocytic leukemia protein 1

1

9

Small-scale

0.508

High

401433

JUN
Transcription factor Jun

1

4

Small-scale

0.501

High

414741

CDK1
Cyclin-dependent kinase 1

1

3

Small-scale

0.501

High

620344

HDAC1
Histone deacetylase 1

1

15

Small-scale

0.501

High

620399

KAT2A
Histone acetyltransferase KAT2A

1

18

Small-scale

0.501

High

499536

CH60
60 kDa heat shock protein, mitochondrial

1

3

High-throughput

0.500

High

518585

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

2

High-throughput

0.500

High

620307

LONM
Lon protease homolog, mitochondrial

1

2

High-throughput

0.500

High

620312

EMD
Emerin

1

2

High-throughput

0.500

High

620316

SYMC
Methionine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.500

High

620355

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.500

High

268402

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.479

High

452627

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.479

High

620322

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.479

High

131692

BCL9
B-cell CLL/lymphoma 9 protein

1

15

High-throughput

0.479

High

146158

ARI1A
AT-rich interactive domain-containing protein 1A

1

15

High-throughput

0.479

High

152589

KMT2D
Histone-lysine N-methyltransferase 2D

1

16

High-throughput

0.479

High

164185

ZN609
Zinc finger protein 609

1

6

High-throughput

0.479

High

167135

ZN536
Zinc finger protein 536

1

5

High-throughput

0.479

High

170258

TIF1A
Transcription intermediary factor 1-alpha

1

13

High-throughput

0.479

High

177195

HDAC3
Histone deacetylase 3

1

15

Small-scale

0.479

High

183065

KDM6A
Lysine-specific demethylase 6A

1

7

High-throughput

0.479

High

231204

ZEB2
Zinc finger E-box-binding homeobox 2

1

3

High-throughput

0.479

High

232003

KDM1A
Lysine-specific histone demethylase 1A

1

12

High-throughput

0.479

High

245560

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

9

High-throughput

0.479

High

261404

NCOR1
Nuclear receptor corepressor 1

1

17

High-throughput

0.479

High

277940

PIAS1
E3 SUMO-protein ligase PIAS1

1

2

High-throughput

0.479

High

318574

EYA4
Eyes absent homolog 4

1

10

High-throughput

0.479

High

321705

WIZ
Protein Wiz

1

3

High-throughput

0.479

High

331444

ACL6A
Actin-like protein 6A

1

1

High-throughput

0.479

High

379026

MYCN
N-myc proto-oncogene protein

1

2

High-throughput

0.479

High

473470

ATX1L
Ataxin-1-like

1

1

High-throughput

0.479

High

515333

CDK4
Cyclin-dependent kinase 4

1

5

Small-scale

0.479

High

550318

ZEP1
Zinc finger protein 40

1

4

High-throughput

0.479

High

590124

CCNA2
Cyclin-A2

1

1

Small-scale

0.479

High

620295

COT2
COUP transcription factor 2

1

8

Small-scale

0.479

High

620296

CDK2
Cyclin-dependent kinase 2

1

3

Small-scale

0.479

High

620304

BMI1
Polycomb complex protein BMI-1

1

16

High-throughput

0.479

High

620308

ZEB1
Zinc finger E-box-binding homeobox 1

1

5

High-throughput

0.479

High

620309

CUX1
Homeobox protein cut-like 1

1

11

High-throughput

0.479

High

620311

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

11

High-throughput

0.479

High

620313

SMCA2
Probable global transcription activator SNF2L2

1

20

High-throughput

0.479

High

620314

SMCA4
Transcription activator BRG1

1

20

High-throughput

0.479

High

620315

ATX1
Ataxin-1

1

1

High-throughput

0.479

High

620319

DCAF7
DDB1- and CUL4-associated factor 7

1

9

High-throughput

0.479

High

620321

H4
Histone H4

1

1

High-throughput

0.479

High

620325

SSBP2
Single-stranded DNA-binding protein 2

1

1

High-throughput

0.479

High

620328

SATB1
DNA-binding protein SATB1

1

4

High-throughput

0.479

High

620329

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

620330

TLE3
Transducin-like enhancer protein 3

1

17

High-throughput

0.479

High

620331

TLE4
Transducin-like enhancer protein 4

1

20

High-throughput

0.479

High

620334

RING1
E3 ubiquitin-protein ligase RING1

1

18

High-throughput

0.479

High

620335

TLE5
TLE family member 5

1

10

High-throughput

0.479

High

620339

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

3

High-throughput

0.479

High

620341

FOXC1
Forkhead box protein C1

1

15

High-throughput

0.479

High

620345

CUL1
Cullin-1

1

3

Small-scale

0.479

High

620348

NCOA6
Nuclear receptor coactivator 6

1

18

High-throughput

0.479

High

620350

ARI5B
AT-rich interactive domain-containing protein 5B

1

18

High-throughput

0.479

High

620351

RBBP5
Retinoblastoma-binding protein 5

1

6

High-throughput

0.479

High

620352

SSXT
Protein SSXT

1

14

High-throughput

0.479

High

620354

ZFHX3
Zinc finger homeobox protein 3

1

6

High-throughput

0.479

High

620361

ARI4B
AT-rich interactive domain-containing protein 4B

1

18

High-throughput

0.479

High

620365

ARID2
AT-rich interactive domain-containing protein 2

1

13

High-throughput

0.479

High

620367

NIPBL
Nipped-B-like protein

1

6

High-throughput

0.479

High

620368

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

15

High-throughput

0.479

High

620370

BCOR
BCL-6 corepressor

1

3

High-throughput

0.479

High

620371

PAXI1
PAX-interacting protein 1

1

7

High-throughput

0.479

High

620372

ASXL2
Putative Polycomb group protein ASXL2

1

6

High-throughput

0.479

High

620374

PCGF5
Polycomb group RING finger protein 5

1

16

High-throughput

0.479

High

620375

LDB1
LIM domain-binding protein 1

1

3

High-throughput

0.479

High

620376

PB1
Protein polybromo-1

1

15

High-throughput

0.479

High

620377

ZFHX4
Zinc finger homeobox protein 4

1

5

High-throughput

0.479

High

620381

ARI3B
AT-rich interactive domain-containing protein 3B

1

18

High-throughput

0.479

High

620383

YAF2
YY1-associated factor 2

1

3

High-throughput

0.479

High

620384

RYBP
RING1 and YY1-binding protein

1

3

High-throughput

0.479

High

620385

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

620386

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

620387

KDM2B
Lysine-specific demethylase 2B

1

2

High-throughput

0.479

High

620389

SMRC2
SWI/SNF complex subunit SMARCC2

1

20

High-throughput

0.479

High

620390

CHD6
Chromodomain-helicase-DNA-binding protein 6

1

16

High-throughput

0.479

High

620391

MORC4
MORC family CW-type zinc finger protein 4

1

2

High-throughput

0.479

High

620393

FOG2
Zinc finger protein ZFPM2

1

12

High-throughput

0.479

High

620395

ZN516
Zinc finger protein 516

1

3

High-throughput

0.479

High

620396

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

620397

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

620400

SMRC1
SWI/SNF complex subunit SMARCC1

1

19

High-throughput

0.479

High

620401

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

10

High-throughput

0.479

High

620403

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

12

High-throughput

0.479

High

620406

ZBTB9
Zinc finger and BTB domain-containing protein 9

1

8

High-throughput

0.479

High

620407

ZN503
Zinc finger protein 503

1

3

High-throughput

0.479

High

620408

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

7

High-throughput

0.479

High

620409

EHMT2
Histone-lysine N-methyltransferase EHMT2

1

3

High-throughput

0.479

High

620411

CIC
Protein capicua homolog

1

18

High-throughput

0.479

High

620412

RING2
E3 ubiquitin-protein ligase RING2

1

17

High-throughput

0.479

High

620414

ARI3A
AT-rich interactive domain-containing protein 3A

1

18

High-throughput

0.479

High

620415

PCGF1
Polycomb group RING finger protein 1

1

16

High-throughput

0.479

High

620417

SSBP3
Single-stranded DNA-binding protein 3

1

7

High-throughput

0.479

High

620419

TBL1R
F-box-like/WD repeat-containing protein TBL1XR1

1

10

High-throughput

0.479

High

620420

SP130
Histone deacetylase complex subunit SAP130

1

6

High-throughput

0.479

High

620422

FOXP1
Forkhead box protein P1

1

15

High-throughput

0.479

High

620423

ZN644
Zinc finger protein 644

1

3

High-throughput

0.479

High

620424

ZN703
Zinc finger protein 703

1

7

High-throughput

0.479

High

620425

EHMT1
Histone-lysine N-methyltransferase EHMT1

1

3

High-throughput

0.479

High

620429

HM20A
High mobility group protein 20A

1

19

High-throughput

0.479

High

620430

BRD7
Bromodomain-containing protein 7

1

18

High-throughput

0.479

High

620431

TF7L2
Transcription factor 7-like 2

1

18

High-throughput

0.479

High

620432

SALL1
Sal-like protein 1

1

5

High-throughput

0.479

High

620434

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

20

High-throughput

0.479

High

620435

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

17

High-throughput

0.479

High

620436

RCOR3
REST corepressor 3

1

20

High-throughput

0.479

High

620438

SIX4
Homeobox protein SIX4

1

6

High-throughput

0.479

High

620439

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

620440

IKZF3
Zinc finger protein Aiolos

1

1

High-throughput

0.479

High

620441

ZN608
Zinc finger protein 608

1

4

High-throughput

0.479

High

620442

PRR12
Proline-rich protein 12

1

11

High-throughput

0.479

High

620443

SATB2
DNA-binding protein SATB2

1

4

High-throughput

0.479

High

620444

HDAC5
Histone deacetylase 5

1

20

Small-scale

0.479

High

620446

ZN281
Zinc finger protein 281

1

3

High-throughput

0.479

High

620449

NCOR2
Nuclear receptor corepressor 2

1

18

High-throughput

0.479

High

620450

NCOA3
Nuclear receptor coactivator 3

1

5

High-throughput

0.479

High

609177

FGFR3
Fibroblast growth factor receptor 3

1

2

High-throughput

0.470

High

620326

PR20C
Proline-rich protein 20C

1

1

High-throughput

0.470

High

620359

KRA63
Keratin-associated protein 6-3

1

1

High-throughput

0.470

High

620323

RBX1
E3 ubiquitin-protein ligase RBX1

1

0

Small-scale

0.458

High

620364

BRM1L
Breast cancer metastasis-suppressor 1-like protein

1

0

High-throughput

0.458

High

620394

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

620405

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

620416

PAGR1
PAXIP1-associated glutamate-rich protein 1

1

0

High-throughput

0.458

High

620421

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

0

High-throughput

0.458

High

620428

SHCAF
SIN3-HDAC complex-associated factor

1

0

High-throughput

0.458

High

428665

TRY1
Serine protease 1

1

1

High-throughput

0.457

High

620337

LG3BP
Galectin-3-binding protein

1

1

High-throughput

0.457

High

620347

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

1

High-throughput

0.457

High

620433

GRHL1
Grainyhead-like protein 1 homolog

1

1

High-throughput

0.445

High

620317

KR103
Keratin-associated protein 10-3

1

6

High-throughput

0.439

High

620327

PR20A
Proline-rich protein 20A

1

1

High-throughput

0.439

High

620349

GSE1
Genetic suppressor element 1

1

2

High-throughput

0.437

High

620357

QSER1
Glutamine and serine-rich protein 1

1

11

High-throughput

0.437

High

620362

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

4

High-throughput

0.437

High

620363

PRC2B
Protein PRRC2B

1

12

High-throughput

0.437

High

620392

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

4

High-throughput

0.437

High

620426

FBRS
Probable fibrosin-1

1

3

High-throughput

0.437

High

620427

FBSL
Fibrosin-1-like protein

1

3

High-throughput

0.437

High

620358

KR212
Keratin-associated protein 21-2

2

0

High-throughput

0.316

High

620378

KR111
Keratin-associated protein 11-1

2

0

High-throughput

0.316

High

620379

KRA81
Keratin-associated protein 8-1

2

0

High-throughput

0.316

High

620380

KRA71
Keratin-associated protein 7-1

2

0

High-throughput

0.316

High

620366

K1C40
Keratin, type I cytoskeletal 40

1

0

High-throughput

0.299

High

620369

ATL4
ADAMTS-like protein 4

1

0

High-throughput

0.299

High


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Last updated: 15 Jul 2024