Interactor 1: ABCG8 (Q9H221)
ATP-binding cassette sub-family G member 8 (EC 7.6.2.-) (Sterolin-2)
Gene: ABCG8

Interactor 2: ABCG5 (Q9H222)
ATP-binding cassette sub-family G member 5 (EC 7.6.2.-) (Sterolin-1)
Gene: ABCG5

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.871

The method score is based on:

Property Details
Experiments 12208867, 27144356, 16870176
Identification Methods affinity chromatography technology, comigration in non denaturing gel electrophoresis, pull down, molecular sieving, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains ABC2_membrane~ABC2_membrane, ABC2_membrane~ABC_tran, ABC2_membrane_7~ABC2_membrane_7, ABC2_membrane_7~ABC_tran, ABC_tran~ABC_tran
Common GO terms GO:0005524 - ATP binding
GO:0005886 - plasma membrane
GO:0007584 - response to nutrient
GO:0009410 - response to xenobiotic stimulus
GO:0010949 - negative regulation of intestinal phytosterol absorption
and 18 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 673
Hs

1 651
+ At
+ Hs
+ At
+ Hs
+ At
+ Hs
+ At
+ Hs
+ Hs
+ Dm
+ Zm
+ At
+ Zm

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Last updated: 15 Jul 2024