Interactor 1: ABCG8 (Q9H221)
ATP-binding cassette sub-family G member 8 (EC 7.6.2.-) (Sterolin-2)
Gene: ABCG8
Interactor 2: ABCG5 (Q9H222)
ATP-binding cassette sub-family G member 5 (EC 7.6.2.-) (Sterolin-1)
Gene: ABCG5
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.75 | 1.00 | 0.871 |
The method score is based on:
Property | Details |
---|---|
Experiments | 12208867, 27144356, 16870176 |
Identification Methods | affinity chromatography technology, comigration in non denaturing gel electrophoresis, pull down, molecular sieving, x-ray crystallography, anti tag coimmunoprecipitation |
Interaction Type | physical association, direct interaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | ABC2_membrane~ABC2_membrane, ABC2_membrane~ABC_tran, ABC2_membrane_7~ABC2_membrane_7, ABC2_membrane_7~ABC_tran, ABC_tran~ABC_tran |
Common GO terms | GO:0005524 - ATP binding GO:0005886 - plasma membrane GO:0007584 - response to nutrient GO:0009410 - response to xenobiotic stimulus GO:0010949 - negative regulation of intestinal phytosterol absorption and 18 others more... |
Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024