HitPredict

Interactor 1: SPTN4 (Q9H254)
Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)
Gene: SPTBN4

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 2564 Hs			1 1124
+	Hs
		211670 ACTN4_HUMAN (60-639): 2.57e-113: 386: 39.93		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		725703 ACTN2_HUMAN (60-648): 9.1e-110: 375: 39.41		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		963430 SPTB2_HUMAN (624-2551): 4.56e-61: 235: 17.42		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		164668 SPTN2_HUMAN (507-2546): 2.8e-51: 203: 18.94		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1045536 SPTN1_HUMAN (259-1728): 1.07e-47: 191: 15.07		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		506845 SPTB1_HUMAN (1693-2459): 1.21e-17: 92.9: 11.98		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1068674 PLEC_HUMAN (233-1186): 4.07e-17: 91.3: 11.29		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		521622 ACTN1_HUMAN (1813-2273): 3.24e-14: 80.9: 10.24		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		993298 ACTN3_HUMAN (1817-2273): 1.6e-10: 69: 12.85		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1343798 MACF1_HUMAN (887-1821): 3.14e-10: 68.7: 13.90		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		974153 DYST_HUMAN (971-1734): 2.66e-10: 68.7: 12.78		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		513898 DMD_HUMAN (254-1241): 2.74e-09: 65.5: 9.46		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Dm
		527106 SPTCA_DROME (249-2435): 3.23e-76: 285: 15.59		ANLN_DROME (542-1112): 1.6e-160: 511: 29.84