HitPredict

Interactor 1: PININ (Q9H307)
Pinin (140 kDa nuclear and cell adhesion-related phosphoprotein) (Desmosome-associated protein) (Domain-rich serine protein) (DRS protein) (DRSP) (Melanoma metastasis clone A protein) (Nuclear protein SDK3) (SR-like protein)
Gene: PNN

Interactor 2: PPIE (Q9UNP9)
Peptidyl-prolyl cis-trans isomerase E (PPIase E) (EC 5.2.1.8) (Cyclophilin E) (Cyclophilin-33) (Rotamase E)
Gene: PPIE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0005886 - plasma membrane GO:0016607 - nuclear speck and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 717 Hs			1 301
+	Hs
		369 PININ_HUMAN (1-717): 3.37e-144: 440: 100.00		PAL4E_HUMAN (139-300): 1.82e-67: 209: 61.11
+	Hs
		483817 PININ_HUMAN (1-717): 3.37e-144: 440: 100.00		PAL4F_HUMAN (139-300): 1.82e-67: 209: 61.11
+	Hs
		923783 PININ_HUMAN (1-717): 3.37e-144: 440: 100.00		PPIA_HUMAN (137-300): 3.31e-63: 198: 66.46