Protein: RRP3
ATP-dependent rRNA helicase RRP3 (EC 3.6.4.13) (Ribosomal RNA-processing protein 3)

Gene: RRP3
Organism: Saccharomyces cerevisiae S288C
Interactions: 56
UniProt ID: P38712

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

802772

ESF1
Pre-rRNA-processing protein ESF1

2

3

High-throughput

0.628

High

594352

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

3

High-throughput

0.618

High

682268

SPB4
ATP-dependent rRNA helicase SPB4

1

19

High-throughput

0.618

High

802759

RS12
Small ribosomal subunit protein eS12

1

5

High-throughput

0.618

High

802766

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.618

High

802767

DHR1
Probable ATP-dependent RNA helicase DHR1

1

11

High-throughput

0.618

High

802781

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.618

High

798202

ENP1
Essential nuclear protein 1

2

6

High-throughput

0.584

High

802779

SAS10
Something about silencing protein 10

1

2

High-throughput

0.541

High

721912

XPO1
Exportin-1

1

17

High-throughput

0.536

High

802768

KU80
ATP-dependent DNA helicase II subunit 2

1

5

High-throughput

0.536

High

802754

LCP5
U3 small nucleolar ribonucleoprotein protein LCP5

1

0

High-throughput

0.518

High

802761

ESF2
Pre-rRNA-processing protein ESF2

1

5

High-throughput

0.515

High

518010

SSBP1
Single-stranded nucleic acid-binding protein

1

8

High-throughput

0.501

High

802753

RV167
Reduced viability upon starvation protein 167

1

2

High-throughput

0.494

High

743521

RU1A
U1 small nuclear ribonucleoprotein A

1

2

High-throughput

0.481

High

149741

RS9A
Small ribosomal subunit protein uS4A

1

8

High-throughput

0.479

High

433619

RL26A
Large ribosomal subunit protein uL24A

1

8

High-throughput

0.479

High

435065

RS3
Small ribosomal subunit protein uS3

1

6

High-throughput

0.479

High

435940

RS13
Small ribosomal subunit protein uS15

1

5

High-throughput

0.479

High

441886

RS14A
Small ribosomal subunit protein uS11A

1

7

High-throughput

0.479

High

455040

RS19A
Small ribosomal subunit protein eS19A

1

7

High-throughput

0.479

High

512987

RS8A
Small ribosomal subunit protein eS8A

1

6

High-throughput

0.479

High

670667

SIS1
Protein SIS1

1

6

High-throughput

0.479

High

674599

RS2
Small ribosomal subunit protein uS5

1

9

High-throughput

0.479

High

677377

KRR1
KRR1 small subunit processome component

1

6

High-throughput

0.479

High

706998

TF2B
Transcription initiation factor IIB

1

7

High-throughput

0.479

High

734958

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

4

High-throughput

0.479

High

778306

RS27A
Small ribosomal subunit protein eS27A

1

5

High-throughput

0.479

High

802146

RS20
Small ribosomal subunit protein uS10

1

9

High-throughput

0.479

High

802755

ULP2
Ubiquitin-like-specific protease 2

1

6

High-throughput

0.479

High

802756

DSN1
Kinetochore-associated protein DSN1

1

5

High-throughput

0.479

High

802757

UTP10
U3 small nucleolar RNA-associated protein 10

1

5

High-throughput

0.479

High

802758

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

3

Small-scale

0.479

High

802760

HST2
NAD-dependent protein deacetylase HST2

1

4

High-throughput

0.479

High

802762

APJ1
J domain-containing protein APJ1

1

5

High-throughput

0.479

High

802764

RS15
Small ribosomal subunit protein uS19

1

6

High-throughput

0.479

High

802769

UTP14
U3 small nucleolar RNA-associated protein 14

1

4

High-throughput

0.479

High

802770

TAF7
Transcription initiation factor TFIID subunit 7

1

1

High-throughput

0.479

High

802771

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

3

High-throughput

0.479

High

802773

NOC4
Nucleolar complex protein 4

1

12

High-throughput

0.479

High

802775

SGO1
Shugoshin

1

4

High-throughput

0.479

High

802776

MCA1
Metacaspase-1

1

2

High-throughput

0.479

High

802777

RS10A
Small ribosomal subunit protein eS10A

1

6

High-throughput

0.479

High

802780

RIO1
Serine/threonine-protein kinase RIO1

1

11

High-throughput

0.479

High

802765

GIS1
Transcriptional activator/repressor GIS1

1

0

High-throughput

0.458

High

802763

SEN1
Helicase SEN1

1

7

Small-scale

0.445

High

383680

RS17A
Small ribosomal subunit protein eS17A

1

6

High-throughput

0.437

High

503021

RS22A
Small ribosomal subunit protein uS8A

1

7

High-throughput

0.437

High

504190

RL31A
Large ribosomal subunit protein eL31A

1

10

High-throughput

0.437

High

514618

RS18A
Small ribosomal subunit protein uS13A

1

6

High-throughput

0.437

High

747341

RSSA1
Small ribosomal subunit protein uS2A

1

12

High-throughput

0.437

High

794967

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

802752

LAA1
AP-1 accessory protein LAA1

1

6

High-throughput

0.437

High

802774

VAM6
Vacuolar morphogenesis protein 6

1

5

High-throughput

0.437

High

802778

TMA46
Translation machinery-associated protein 46

1

1

High-throughput

0.437

High


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Last updated: 11Aug2025