HitPredict

Interactor 1: TXNIP (Q9H3M7)
Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1)
Gene: TXNIP

Interactor 2: TXNIP (Q9H3M7)
Thioredoxin-interacting protein (Thioredoxin-binding protein 2) (Vitamin D3 up-regulated protein 1)
Gene: TXNIP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 24389582, 31669268
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Arrestin_C~Arrestin_C, Arrestin_C~Arrestin_N, Arrestin_N~Arrestin_N
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0004857 - enzyme inhibitor activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006606 - protein import into nucleus
and 18 others

more...
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 391
Hs

1 391
+ Hs
+ Ce
+ Ce
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Rn
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024