HitPredict

Interactor 1: FNDC5 (Q8NAU1)
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) [Cleaved into: Irisin]
Gene: FNDC5

Interactor 2: EVPL (Q92817)
Envoplakin (210 kDa cornified envelope precursor protein) (210 kDa paraneoplastic pemphigus antigen) (p210)
Gene: EVPL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 260 Hs			1 2033
+	Hs
		248740 FNDC5_HUMAN (1-260): 1.88e-174: 482: 100.00		PEPL_HUMAN (1-902): 7.79e-24: 112: 9.03
+	Mm
		1317485 FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23		MYH9_MOUSE (1377-1952): 5.01e-19: 96.9: 10.54
+	Mm
		1317868 FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23		PLEC_MOUSE (1836-2015): 1.92e-11: 72.2: 35.00
+	Mm
		98072 FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23		DESP_MOUSE (2-486): 1.16e-10: 69.5: 5.44