HitPredict

Interactor 1: AT133 (Q9H7F0)
Polyamine-transporting ATPase 13A3 (ATPase family homolog up-regulated in senescence cells 1) (Putrescine transporting ATPase) (EC 7.6.2.16)
Gene: ATP13A3

Interactor 2: C5AR2 (Q9P296)
C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77)
Gene: C5AR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1226 Hs			1 337
+	Hs
		626594 AT133_HUMAN (1-1226): 0: 1057: 100.00		FPR2_HUMAN (33-335): 5.12e-78: 244: 28.27
+	Hs
		600845 AT133_HUMAN (1-1226): 0: 1057: 100.00		C5AR1_HUMAN (3-336): 2.69e-63: 206: 34.48
+	Hs
		208478 AT133_HUMAN (1-1226): 0: 1057: 100.00		OX2R_HUMAN (2-333): 5.5e-62: 205: 13.85
+	Hs
		849708 AT133_HUMAN (1-1226): 0: 1057: 100.00		CCR6_HUMAN (2-335): 2.32e-59: 197: 17.48
+	Hs
		626825 AT132_HUMAN (21-1204): 0: 847: 40.27		ACKR3_HUMAN (8-307): 1.86e-75: 237: 21.47
+	Hs
		895742 AT132_HUMAN (21-1204): 0: 847: 40.27		CXCR4_HUMAN (2-298): 9.99e-72: 228: 22.58
+	Hs
		530832 AT1A3_HUMAN (151-1172): 0: 680: 17.78		FPR2_HUMAN (33-335): 5.12e-78: 244: 28.27
+	Hs
		530862 AT1A3_HUMAN (151-1172): 0: 680: 17.78		CXCR4_HUMAN (2-298): 9.99e-72: 228: 22.58
+	Hs
		392982 AT1A1_HUMAN (151-1172): 0: 690: 18.99		ADRB2_HUMAN (2-330): 1.21e-65: 214: 15.63
+	Hs
		530988 AT1A3_HUMAN (151-1172): 0: 680: 17.78		C5AR2_HUMAN (1-337): 1.47e-65: 211: 100.00
+	Hs
		530839 AT1A3_HUMAN (151-1172): 0: 680: 17.78		NK3R_HUMAN (1-335): 3.01e-63: 209: 16.90
+	Hs
		530829 AT1A3_HUMAN (151-1172): 0: 680: 17.78		C5AR1_HUMAN (3-336): 2.69e-63: 206: 34.48
+	Hs
		530844 AT1A3_HUMAN (151-1172): 0: 680: 17.78		OPRX_HUMAN (5-323): 1.76e-61: 202: 22.39
+	Hs
		626508 AT12A_HUMAN (112-1174): 0: 611: 17.28		FPR2_HUMAN (33-335): 5.12e-78: 244: 28.27
+	Hs
		598929 AT12A_HUMAN (112-1174): 0: 611: 17.28		FPR1_HUMAN (34-326): 2.06e-75: 237: 27.85
+	Hs
		674882 AT131_HUMAN (26-1175): 0: 623: 22.23		AGTR1_HUMAN (31-329): 2.17e-62: 204: 23.03
+	Hs
		666302 AT12A_HUMAN (112-1174): 0: 611: 17.28		NK3R_HUMAN (1-335): 3.01e-63: 209: 16.90
+	Hs
		849710 AT131_HUMAN (26-1175): 0: 623: 22.23		CCR6_HUMAN (2-335): 2.32e-59: 197: 17.48
+	Hs
		600754 AT12A_HUMAN (112-1174): 0: 611: 17.28		C5AR1_HUMAN (3-336): 2.69e-63: 206: 34.48
+	Hs
		208450 AT12A_HUMAN (112-1174): 0: 611: 17.28		OX2R_HUMAN (2-333): 5.5e-62: 205: 13.85