Protein: DCR1C
Protein artemis (EC 3.1.-.-) (DNA cross-link repair 1C protein) (Protein A-SCID) (SNM1 homolog C) (hSNM1C) (SNM1-like protein)

Gene: DCR1C, DCLRE1C
Organism: Homo sapiens
Interactions: 42
UniProt ID: Q96SD1

Gene Ontology (top 5):
GO:0000014 - single-stranded DNA endodeoxyribonuclease activity
GO:0000723 - telomere maintenance
GO:0002250 - adaptive immune response
GO:0003684 - damaged DNA binding
GO:0004519 - endonuclease activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1008297

PRKDC
DNA-dependent protein kinase catalytic subunit

7

4

Small-scale

0.969

High

559464

XRCC5
X-ray repair cross-complementing protein 5

2

0

Small-scale

0.716

High

930353

AAKG1
5'-AMP-activated protein kinase subunit gamma-1

4

2

High-throughput

0.694

High

930782

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

4

2

High-throughput

0.694

High

1095447

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

4

2

High-throughput

0.694

High

1402693

AAKB1
5'-AMP-activated protein kinase subunit beta-1

4

1

High-throughput

0.694

High

177299

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

3

1

High-throughput

0.656

High

225672

AAKB2
5'-AMP-activated protein kinase subunit beta-2

3

1

High-throughput

0.656

High

1402689

AAKG2
5'-AMP-activated protein kinase subunit gamma-2

3

1

High-throughput

0.656

High

892716

DNLI4
DNA ligase 4

2

0

Small-scale

0.635

High

1157881

DDB1
DNA damage-binding protein 1

2

8

Small-scale

0.624

High

273705

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

3

1

High-throughput

0.599

High

1333072

ANR52
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C

3

1

High-throughput

0.599

High

1402692

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

3

1

High-throughput

0.599

High

651707

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

2

0

High-throughput

0.585

High

718614

CDC27
Cell division cycle protein 27 homolog

2

0

High-throughput

0.585

High

892920

MRE11
Double-strand break repair protein MRE11

2

1

Small-scale

0.584

High

1369744

RAD50
DNA repair protein RAD50

2

2

Small-scale

0.584

High

1102231

ATM
Serine-protein kinase ATM

1

4

Small-scale

0.561

High

1363077

DDB2
DNA damage-binding protein 2

1

5

Small-scale

0.561

High

262116

NBN
Nibrin

2

0

Small-scale

0.559

High

1402690

DDX20
Probable ATP-dependent RNA helicase DDX20

2

0

High-throughput

0.559

High

355024

CHK2
Serine/threonine-protein kinase Chk2

1

2

High-throughput

0.536

High

1357881

CTF18
Chromosome transmission fidelity protein 18 homolog

1

0

High-throughput

0.513

High

1109494

ATR
Serine/threonine-protein kinase ATR

1

4

Small-scale

0.501

High

1398675

JKIP1
Janus kinase and microtubule-interacting protein 1

1

2

High-throughput

0.489

High

857355

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

0

Small-scale

0.480

High

799421

BRCA1
Breast cancer type 1 susceptibility protein

1

5

Small-scale

0.479

High

1063554

GOGA2
Golgin subfamily A member 2

1

1

High-throughput

0.479

High

1380105

FBXW7
F-box/WD repeat-containing protein 7

1

3

Small-scale

0.479

High

1104929

XRCC4
DNA repair protein XRCC4

1

0

Small-scale

0.464

High

414460

P53
Cellular tumor antigen p53

1

0

High-throughput

0.458

High

573876

CCNB1
G2/mitotic-specific cyclin-B1

1

0

Small-scale

0.458

High

1401311

PASK
PAS domain-containing serine/threonine-protein kinase

1

1

High-throughput

0.437

High

67499

ZSWM8
Zinc finger SWIM domain-containing protein 8

2

0

High-throughput

0.318

High

1089258

TRI26
Tripartite motif-containing protein 26

2

0

High-throughput

0.318

High

1158075

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

2

0

High-throughput

0.318

High

1347804

SPT20
Spermatogenesis-associated protein 20

2

0

High-throughput

0.318

High

1402691

AKA11
A-kinase anchor protein 11

2

0

High-throughput

0.318

High

138939

USP9Y
Ubiquitin carboxyl-terminal hydrolase 9Y

1

0

High-throughput

0.279

Low

844272

MTHR
Methylenetetrahydrofolate reductase

1

0

High-throughput

0.279

Low

725445

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025