HitPredict

Interactor 1: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Interactor 2: PRP19 (Q9UMS4)
Pre-mRNA-processing factor 19 (EC 2.3.2.27) (Nuclear matrix protein 200) (PRP19/PSO4 homolog) (hPso4) (RING-type E3 ubiquitin transferase PRP19) (Senescence evasion factor)
Gene: PRPF19

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 914 Hs			1 504
+	Hs
		1288311 ECT2_HUMAN (1-914): 0: 886: 100.00		SNR40_HUMAN (298-504): 7e-58: 197: 21.91
+	Hs
		560889 ECT2_HUMAN (1-914): 0: 886: 100.00		GBB3_HUMAN (297-504): 4.81e-49: 173: 17.76
+	Hs
		903526 ECT2_HUMAN (1-914): 0: 886: 100.00		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		1049720 ARHG7_HUMAN (309-913): 4.64e-90: 305: 11.83		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		1016930 AKP13_HUMAN (274-912): 7.43e-83: 295: 13.83		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		1273255 ARHG2_HUMAN (249-775): 2e-83: 291: 15.02		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06
+	Hs
		1231083 ARG28_HUMAN (216-807): 7.17e-88: 309: 12.32		POC1B_HUMAN (109-365): 2.73e-43: 161: 15.44
+	Hs
		1266889 TOPB1_HUMAN (92-458): 8.82e-90: 314: 23.10		NLE1_HUMAN (93-333): 6.85e-38: 146: 14.86
+	Hs
		903416 ARHG2_HUMAN (249-775): 2e-83: 291: 15.02		WDR5_HUMAN (93-333): 2.8e-41: 152: 15.48
+	Hs
		1254029 PREX1_HUMAN (406-861): 1.32e-78: 282: 18.47		NLE1_HUMAN (93-333): 6.85e-38: 146: 14.86
+	Hs
		164142 ARHGA_HUMAN (436-704): 1.71e-23: 109: 29.33		FBXW7_HUMAN (88-458): 1.1e-73: 248: 18.06