HitPredict

Interactor 1: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Interactor 2: ASH2L (Q9UBL3)
Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein)
Gene: ASH2L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.69 1.00 0.834

The method score is based on:

Property Details
Experiments 24705355, 20085832
Identification Methods affinity chromatography technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C~SPRY
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0008013 - beta-catenin binding
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0071339 - MLL1 complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 2581
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024