Protein: SCD6
Protein SCD6 (Suppressor of clathrin deficiency protein 6)

Gene: SCD6
Organism: Saccharomyces cerevisiae S288C
Interactions: 83
UniProt ID: P45978

Gene Ontology (top 5):
GO:0000932 - P-body
GO:0003729 - mRNA binding
GO:0005737 - cytoplasm
GO:0010494 - cytoplasmic stress granule
GO:0031370 - eukaryotic initiation factor 4G binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

853602

DCP2
m7GpppN-mRNA hydrolase

7

2

Small-scale

0.741

High

815152

IF4F1
Eukaryotic initiation factor 4F subunit p150

6

1

Small-scale

0.726

High

812067

DHH1
ATP-dependent RNA helicase DHH1

3

7

Small-scale

0.674

High

853612

DCP1
mRNA-decapping enzyme subunit 1

4

0

Small-scale

0.649

High

678694

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

3

2

Small-scale

0.645

High

792849

ANM1
Protein arginine N-methyltransferase 1

4

5

Small-scale

0.636

High

806304

KOG1
Target of rapamycin complex 1 subunit KOG1

2

1

Small-scale

0.619

High

816656

EDC3
Enhancer of mRNA-decapping protein 3

2

1

Small-scale

0.619

High

403554

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

1

Small-scale

0.584

High

435179

RS3
Small ribosomal subunit protein uS3

2

1

Small-scale

0.584

High

819090

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

Small-scale

0.571

High

853596

SCD6
Protein SCD6

1

1

Small-scale

0.561

High

853605

EBS1
Nonsense-mediated mRNA decay factor EBS1

2

0

Small-scale

0.559

High

818013

LSM4
LSM complex subunit LSM4

1

1

High-throughput

0.541

High

722044

XPO1
Exportin-1

1

4

High-throughput

0.536

High

760657

WHI3
Protein WHI3

1

0

High-throughput

0.518

High

542974

CDC24
Cell division control protein 24

1

0

High-throughput

0.513

High

453964

IF4E
Eukaryotic translation initiation factor 4E

1

2

Small-scale

0.501

High

656520

KC11
Casein kinase I homolog 1

1

1

High-throughput

0.501

High

762839

TOR1
Serine/threonine-protein kinase TOR1

1

2

High-throughput

0.501

High

815308

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

1

Small-scale

0.501

High

853601

ATG1
Serine/threonine-protein kinase ATG1

1

2

High-throughput

0.501

High

721632

RENT1
ATP-dependent helicase NAM7

1

3

Small-scale

0.481

High

743399

TOR2
Serine/threonine-protein kinase TOR2

1

2

High-throughput

0.481

High

803200

RIM4
Meiotic activator RIM4

1

3

Small-scale

0.481

High

853611

SMC4
Structural maintenance of chromosomes protein 4

1

1

Small-scale

0.481

High

436451

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.479

High

438722

SC160
Protein SCP160

1

8

Small-scale

0.479

High

518061

SSBP1
Single-stranded nucleic acid-binding protein

1

2

Small-scale

0.479

High

524343

HSP71
Heat shock protein SSA1

1

1

Small-scale

0.479

High

527007

HSP72
Heat shock protein SSA2

1

1

Small-scale

0.479

High

545331

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

Small-scale

0.479

High

645455

XRN1
5'-3' exoribonuclease 1

1

1

Small-scale

0.479

High

678974

NOT1
General negative regulator of transcription subunit 1

1

1

Small-scale

0.479

High

741833

HSP7F
Heat shock protein homolog SSE1

1

2

Small-scale

0.479

High

747438

RSSA1
Small ribosomal subunit protein uS2A

1

1

Small-scale

0.479

High

795884

LSM2
LSM complex subunit LSM2

1

3

Small-scale

0.479

High

853599

RL4B
Large ribosomal subunit protein uL4B

1

1

Small-scale

0.479

High

853610

YRA1
RNA annealing protein YRA1

1

1

Small-scale

0.479

High

392937

HSP82
ATP-dependent molecular chaperone HSP82

1

0

Small-scale

0.460

High

671655

SCJ1
DnaJ-related protein SCJ1

1

0

Small-scale

0.460

High

739109

PT309
Mitochondrial COX1 translation regulator PET309

1

0

Small-scale

0.460

High

782672

ESL2
EST/SMG-like protein 2

1

0

Small-scale

0.460

High

808802

LYS9
Saccharopine dehydrogenase [NADP(+), L-glutamate-forming]

1

0

Small-scale

0.460

High

853606

GDE
Glycogen debranching enzyme

1

0

Small-scale

0.460

High

853607

GYP1
GTPase-activating protein GYP1

1

0

Small-scale

0.460

High

359273

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

0

Small-scale

0.458

High

365091

KPYK1
Pyruvate kinase 1

1

0

Small-scale

0.458

High

394677

EF1A
Elongation factor 1-alpha

1

0

Small-scale

0.458

High

427332

RLA0
Large ribosomal subunit protein uL10

1

0

Small-scale

0.458

High

512104

RS4A
Small ribosomal subunit protein eS4A

1

0

Small-scale

0.458

High

515277

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.458

High

558778

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

570059

RL3
Large ribosomal subunit protein uL3

1

0

Small-scale

0.458

High

653874

HSP12
12 kDa heat shock protein

1

0

Small-scale

0.458

High

757662

IF4B
Eukaryotic translation initiation factor 4B

1

0

Small-scale

0.458

High

780035

EAP1
Protein EAP1

1

0

Small-scale

0.458

High

795424

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.458

High

799753

IF5
Eukaryotic translation initiation factor 5

1

0

Small-scale

0.458

High

818462

LSM5
LSM complex subunit LSM5

1

0

Small-scale

0.458

High

853598

RS12
Small ribosomal subunit protein eS12

1

0

Small-scale

0.458

High

853600

PSP2
Protein PSP2

1

0

Small-scale

0.458

High

853608

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.458

High

503504

RS28B
Small ribosomal subunit protein eS28B

1

1

Small-scale

0.439

High

853613

RS28A
Small ribosomal subunit protein eS28A

1

1

Small-scale

0.439

High

531791

RL4A
Large ribosomal subunit protein uL4A

1

1

Small-scale

0.437

High

853597

RSSA2
Small ribosomal subunit protein uS2B

1

1

Small-scale

0.437

High

826607

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

736566

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.282

High

738005

ISF1
Increasing suppression factor 1

1

0

Small-scale

0.251

Low

758383

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

Small-scale

0.251

Low

803364

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

0

Small-scale

0.251

Low

812284

ATC3
Phospholipid-transporting ATPase DRS2

1

0

Small-scale

0.251

Low

367997

ENO2
Enolase 2

1

0

Small-scale

0.249

Low

513710

RL2A
Large ribosomal subunit protein uL2A

1

0

Small-scale

0.249

Low

655479

RS3A2
Small ribosomal subunit protein eS1B

1

0

Small-scale

0.249

Low

679816

CDC48
Cell division control protein 48

1

0

High-throughput

0.249

Low

707452

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

812426

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

853603

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

853604

EF3B
Elongation factor 3B

1

0

Small-scale

0.249

Low

853609

ATG9
Autophagy-related protein 9

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025