Interactor 1: PRKN (Q9JK66)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN
Interactor 2: TRIB3 (Q9WTQ6)
Tribbles homolog 3 (TRB-3) (Neuronal cell death-inducible putative kinase)
Gene: TRIB3
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 26224857 |
Identification Methods | affinity chromatography technology |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Pkinase~ubiquitin |
Common GO terms | GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0010506 - regulation of autophagy GO:0019899 - enzyme binding and 4 others more... |
Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024