HitPredict

Interactor 1: DDX3X (O00571)
ATP-dependent RNA helicase DDX3X (EC 3.6.4.13) (CAP-Rf) (DEAD box protein 3, X-chromosomal) (DEAD box, X isoform) (DBX) (Helicase-like protein 2) (HLP2)
Gene: DDX3X

Interactor 2: 1433G (P61981)
14-3-3 protein gamma (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein gamma, N-terminally processed]
Gene: YWHAG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 662 Hs			1 247
+	Hs
		133992 DDX3X_HUMAN (1-662): 0: 614: 100.00		1433F_HUMAN (1-246): 2.5e-135: 382: 86.99
+	Hs
		133969 DDX3X_HUMAN (1-662): 0: 614: 100.00		1433Z_HUMAN (2-245): 2.39e-108: 314: 74.59
+	Hs
		133888 DDX3X_HUMAN (1-662): 0: 614: 100.00		1433T_HUMAN (2-245): 5.53e-105: 305: 70.33
+	Hs
		571384 DDX5_HUMAN (90-658): 2.78e-160: 476: 35.70		1433G_HUMAN (1-247): 3.15e-139: 392: 100.00
+	At
		788599 RH20_ARATH (82-574): 4.47e-153: 453: 38.46		14333_ARATH (1-244): 4.4e-142: 400: 61.79
+	Hs
		571326 DDX5_HUMAN (90-658): 2.78e-160: 476: 35.70		1433S_HUMAN (2-245): 1.86e-98: 289: 65.16