Protein: AVR2B
Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB)

Gene: AVR2B, ACVR2B
Organism: Homo sapiens
Interactions: 96
UniProt ID: Q13705

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001702 - gastrulation with mouth forming second
GO:0001822 - kidney development
GO:0001946 - lymphangiogenesis
GO:0001974 - blood vessel remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

738449

ACV1B
Activin receptor type-1B

4

20

Small-scale

0.881

High

739972

TGFR2
TGF-beta receptor type-2

3

19

High-throughput

0.861

High

793098

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

4

High-throughput

0.861

High

439886

INHBA
Inhibin beta A chain

3

20

Small-scale

0.834

High

674790

GRPR
Gastrin-releasing peptide receptor

2

3

High-throughput

0.811

High

312855

GDF11
Growth/differentiation factor 11

2

20

Small-scale

0.799

High

451820

INHBB
Inhibin beta B chain

2

20

Small-scale

0.789

High

646031

AVR2A
Activin receptor type-2A

2

20

Small-scale

0.789

High

738341

BMR1A
Bone morphogenetic protein receptor type-1A

2

20

Small-scale

0.789

High

771187

CD79B
B-cell antigen receptor complex-associated protein beta chain

2

0

High-throughput

0.770

High

520077

BMP2
Bone morphogenetic protein 2

2

20

Small-scale

0.768

High

155757

GDF8
Growth/differentiation factor 8

2

20

Small-scale

0.702

High

380105

MAS
Proto-oncogene Mas

1

3

High-throughput

0.691

High

452420

PGFRB
Platelet-derived growth factor receptor beta

1

10

High-throughput

0.691

High

489958

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

3

High-throughput

0.691

High

647888

MARK3
MAP/microtubule affinity-regulating kinase 3

1

4

High-throughput

0.691

High

738542

TGFR1
TGF-beta receptor type-1

1

20

High-throughput

0.691

High

968374

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

20

High-throughput

0.691

High

981118

ACVR1
Activin receptor type-1

1

20

High-throughput

0.691

High

994630

DDR1
Epithelial discoidin domain-containing receptor 1

1

20

High-throughput

0.691

High

1026155

PAK1
Serine/threonine-protein kinase PAK 1

1

8

High-throughput

0.691

High

1044912

CNGA3
Cyclic nucleotide-gated channel alpha-3

1

9

High-throughput

0.691

High

1044913

CDC37
Hsp90 co-chaperone Cdc37

1

1

High-throughput

0.691

High

1044918

PKN3
Serine/threonine-protein kinase N3

1

4

High-throughput

0.691

High

1044922

NLRX1
NLR family member X1

1

8

High-throughput

0.691

High

1044936

KIRR1
Kin of IRRE-like protein 1

1

1

High-throughput

0.691

High

946017

DLK1
Protein delta homolog 1

3

3

High-throughput

0.667

High

1044947

CC50A
Cell cycle control protein 50A

3

3

High-throughput

0.667

High

1044933

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.656

High

313007

BMP10
Bone morphogenetic protein 10

1

20

Small-scale

0.647

High

1044939

NODAL
Nodal homolog

1

20

Small-scale

0.647

High

1044950

GDF2
Growth/differentiation factor 2

1

20

Small-scale

0.647

High

1044954

PCDG5
Protocadherin gamma-A5

2

4

High-throughput

0.628

High

1044945

RAB6B
Ras-related protein Rab-6B

1

8

High-throughput

0.618

High

431836

HS90A
Heat shock protein HSP 90-alpha

1

15

High-throughput

0.618

High

438157

HS90B
Heat shock protein HSP 90-beta

1

15

High-throughput

0.618

High

574203

BMP7
Bone morphogenetic protein 7

1

20

Small-scale

0.618

High

602931

BMP6
Bone morphogenetic protein 6

1

20

Small-scale

0.618

High

792920

GDF5
Growth/differentiation factor 5

1

20

Small-scale

0.618

High

1044941

Q9H4D1
Protein kinase

1

6

High-throughput

0.618

High

1044924

IZUM1
Izumo sperm-egg fusion protein 1

2

0

High-throughput

0.602

High

1044940

Q96T11
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to ANKYRIN R

1

5

High-throughput

0.575

High

1044937

LRIQ1
Leucine-rich repeat and IQ domain-containing protein 1

2

20

High-throughput

0.574

High

170539

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

2

1

High-throughput

0.558

High

59851

A4D1W7
Inhibin beta A chain

1

20

Small-scale

0.553

High

154363

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

10

High-throughput

0.536

High

179176

COPT1
High affinity copper uptake protein 1

1

2

High-throughput

0.536

High

622737

IL4RA
Interleukin-4 receptor subunit alpha

1

1

High-throughput

0.536

High

798241

KI3L2
Killer cell immunoglobulin-like receptor 3DL2

1

8

High-throughput

0.536

High

850314

CLCN3
H(+)/Cl(-) exchange transporter 3

1

1

High-throughput

0.536

High

1044914

TTMP
TPA-induced transmembrane protein

1

2

High-throughput

0.536

High

1044916

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

1

High-throughput

0.536

High

1044920

PKHH3
Pleckstrin homology domain-containing family H member 3

1

2

High-throughput

0.536

High

1044923

DEN6A
Protein DENND6A

1

1

High-throughput

0.536

High

1044925

AGRG5
Adhesion G-protein coupled receptor G5

1

2

High-throughput

0.536

High

1044927

I17RC
Interleukin-17 receptor C

1

2

High-throughput

0.536

High

1044928

RN149
E3 ubiquitin-protein ligase RNF149

1

12

High-throughput

0.536

High

1044929

S20A1
Sodium-dependent phosphate transporter 1

1

2

High-throughput

0.536

High

1044930

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

1

11

High-throughput

0.536

High

1044932

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

3

High-throughput

0.536

High

1044934

MRAP2
Melanocortin-2 receptor accessory protein 2

1

5

High-throughput

0.536

High

1044943

MARH7
E3 ubiquitin-protein ligase MARCHF7

1

8

High-throughput

0.536

High

1044944

I17RB
Interleukin-17 receptor B

1

1

High-throughput

0.536

High

1044948

FMN2
Formin-2

1

3

High-throughput

0.536

High

1044951

PCDGG
Protocadherin gamma-B4

1

4

High-throughput

0.536

High

1044955

S12A7
Solute carrier family 12 member 7

1

3

High-throughput

0.536

High

1044956

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

5

High-throughput

0.536

High

1044938

ERBIN
Erbin

1

20

Small-scale

0.527

High

146973

C2C2L
Phospholipid transfer protein C2CD2L

1

0

High-throughput

0.513

High

863065

MVD1
Diphosphomevalonate decarboxylase

1

0

High-throughput

0.513

High

1044915

IQEC2
IQ motif and SEC7 domain-containing protein 2

1

0

High-throughput

0.513

High

1044919

KCNT2
Potassium channel subfamily T member 2

1

0

High-throughput

0.513

High

526889

TDGF1
Protein Cripto

1

7

Small-scale

0.501

High

1044953

FBX7
F-box only protein 7

1

1

High-throughput

0.501

High

68229

HECA2
HEPACAM family member 2

1

3

High-throughput

0.489

High

654317

CALX
Calnexin

1

5

High-throughput

0.489

High

1044931

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

11

High-throughput

0.489

High

1044935

RUSF1
RUS family member 1

1

3

High-throughput

0.489

High

1044942

MANS1
MANSC domain-containing protein 1

1

2

High-throughput

0.489

High

1044946

GINM1
Glycoprotein integral membrane protein 1

1

2

High-throughput

0.489

High

1044949

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

8

High-throughput

0.489

High

883910

SYJ2B
Synaptojanin-2-binding protein

1

4

Small-scale

0.481

High

130879

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

4

Small-scale

0.479

High

167360

SMAD7
Mothers against decapentaplegic homolog 7

1

20

Small-scale

0.479

High

206958

SMAD6
Mothers against decapentaplegic homolog 6

1

20

Small-scale

0.479

High

240387

SNX2
Sorting nexin-2

1

8

Small-scale

0.479

High

571124

EGLN
Endoglin

1

12

Small-scale

0.479

High

1040457

SNX1
Sorting nexin-1

1

9

Small-scale

0.479

High

1044911

SMAD2
Mothers against decapentaplegic homolog 2

1

20

Small-scale

0.479

High

1044917

RGMB
Repulsive guidance molecule B

1

6

Small-scale

0.479

High

1044921

PEG10
Retrotransposon-derived protein PEG10

1

8

Small-scale

0.479

High

1044926

IGSF1
Immunoglobulin superfamily member 1

1

7

Small-scale

0.479

High

1044952

SNX6
Sorting nexin-6

1

8

Small-scale

0.479

High

1017575

FSTL1
Follistatin-related protein 1

1

5

Small-scale

0.457

High

69476

UPK3L
Uroplakin-3b-like protein 1

1

0

High-throughput

0.279

Low

306404

NDUA3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024