HitPredict

Interactor 1: DDB1A (Q9M0V3)
DNA damage-binding protein 1a (UV-damaged DNA-binding protein 1a) (DDB1a)
Gene: DDB1A

Interactor 2: SPA2 (Q9T014)
Protein SPA1-RELATED 2
Gene: SPA2

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	20061554
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CPSF_A~WD40, MMS1_N~WD40
Common GO terms	GO:0005634 - nucleus GO:0009585 - red, far-red light phototransduction GO:0080008 - Cul4-RING E3 ubiquitin ligase complex
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1088 At			1 1036
+	At
		221836 DDB1B_ARATH (1-1088): 0: 1308: 91.27		SPA2_ARATH (1-1036): 0: 923: 100.00
+	At
		1340745 DDB1A_ARATH (1-1088): 0: 1321: 100.00		SPA1_ARATH (10-1036): 0: 678: 40.09
+	At
		221834 DDB1B_ARATH (1-1088): 0: 1308: 91.27		SPA1_ARATH (10-1036): 0: 678: 40.09
+	At
		1338320 DDB1A_ARATH (1-1088): 0: 1321: 100.00		SPA3_ARATH (252-1036): 4.75e-130: 416: 36.43
+	At
		221832 DDB1B_ARATH (1-1088): 0: 1308: 91.27		SPA3_ARATH (252-1036): 4.75e-130: 416: 36.43
+	At
		1277622 DDB1A_ARATH (1-1088): 0: 1321: 100.00		SPA4_ARATH (280-1036): 2.05e-124: 400: 36.66
+	At
		221830 DDB1B_ARATH (1-1088): 0: 1308: 91.27		SPA4_ARATH (280-1036): 2.05e-124: 400: 36.66
+	Hs
		1082292 DDB1_HUMAN (3-1088): 0: 1206: 52.44		COP1_HUMAN (511-1036): 2.89e-81: 282: 36.11
+	Hs
		1082374 DDB1_HUMAN (3-1088): 0: 1206: 52.44		TBL1R_HUMAN (577-981): 3.85e-70: 245: 15.14
+	At
		794497 DDB1A_ARATH (1-1088): 0: 1321: 100.00		COP1_ARATH (814-1035): 3.83e-29: 126: 14.53
+	Hs
		245605 DDB1_HUMAN (3-1088): 0: 1206: 52.44		TBL1X_HUMAN (568-981): 1.3e-66: 237: 13.68
+	Hs
		903254 DDB1_HUMAN (3-1088): 0: 1206: 52.44		WDR5_HUMAN (590-927): 7.15e-69: 235: 17.39
+	At
		221820 DDB1B_ARATH (1-1088): 0: 1308: 91.27		COP1_ARATH (814-1035): 3.83e-29: 126: 14.53
+	Hs
		1082263 DDB1_HUMAN (3-1088): 0: 1206: 52.44		WDR5B_HUMAN (519-843): 6.41e-42: 158: 10.15
+	Hs
		1082327 DDB1_HUMAN (3-1088): 0: 1206: 52.44		SNR40_HUMAN (929-1034): 1.88e-16: 84.1: 12.26
+	Mm
		1112269 DDB1_MOUSE (3-1088): 0: 1207: 52.53		WDR3_MOUSE (924-1036): 2.29e-13: 76.8: 14.16
+	Hs
		1073168 SF3B3_HUMAN (3-1085): 0: 1018: 21.15		NLE1_HUMAN (469-843): 3.26e-36: 145: 12.85
+	Hs
		197009 CPSF1_HUMAN (632-1087): 1.83e-118: 400: 22.72		PRP4_HUMAN (813-1035): 4.83e-39: 154: 16.81
+	Hs
		1014208 CPSF1_HUMAN (632-1087): 1.83e-118: 400: 22.72		NLE1_HUMAN (469-843): 3.26e-36: 145: 12.85