HitPredict

Interactor 1: COP1 (Q8NHY2)
E3 ubiquitin-protein ligase COP1 (EC 2.3.2.27) (Constitutive photomorphogenesis protein 1 homolog) (hCOP1) (RING finger and WD repeat domain protein 2) (RING finger protein 200) (RING-type E3 ubiquitin transferase RFWD2)
Gene: COP1

Interactor 2: XPO7 (Q9UIA9)
Exportin-7 (Exp7) (Ran-binding protein 16)
Gene: XPO7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36897256
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 731 Hs			1 1087
+	Mm
		965404 WDR5_MOUSE (297-625): 1.46e-64: 219: 16.32		XPO7_MOUSE (1-1087): 0: 1231: 99.45
+	Hs
		1066537 RBBP4_HUMAN (512-702): 3.24e-20: 96: 14.49		XPO7_HUMAN (1-1087): 0: 1234: 100.00
+	Hs
		1159041 RBBP7_HUMAN (476-629): 3.9e-12: 70.9: 29.34		XPO7_HUMAN (1-1087): 0: 1234: 100.00
+	Mm
		1222105 RBBP7_MOUSE (476-629): 3.9e-12: 70.9: 29.34		XPO7_MOUSE (1-1087): 0: 1231: 99.45
+	Hs
		173175 FBXW7_HUMAN (390-730): 3.04e-83: 280: 16.33		XPO1_HUMAN (7-1074): 0: 815: 13.35
+	Xl
		1237683 TB1RA_XENLA (229-671): 2.37e-71: 243: 14.98		Q6NS03_XENLA (7-1074): 0: 805: 13.26
+	Hs
		172647 WDR5_HUMAN (297-625): 1.46e-64: 219: 16.32		XPO1_HUMAN (7-1074): 0: 815: 13.35
+	Xl
		1231406 Q6DCY8_XENLA (297-625): 7.01e-64: 217: 16.91		Q6NS03_XENLA (7-1074): 0: 805: 13.26
+	Hs
		172284 PRP4_HUMAN (511-730): 6.67e-41: 159: 16.59		XPO1_HUMAN (7-1074): 0: 815: 13.35
+	Sc
		721870 TAF5_YEAST (150-618): 2.78e-44: 172: 11.58		XPO1_YEAST (7-1073): 0: 775: 14.80
+	Hs
		173205 SNR40_HUMAN (308-447): 1.62e-09: 62.2: 12.08		XPO1_HUMAN (7-1074): 0: 815: 13.35
+	Hs
		220961 FBXW7_HUMAN (390-730): 3.04e-83: 280: 16.33		XPOT_HUMAN (12-229): 2.95e-11: 69.9: 13.84